{"uid":"cap_yWwzLaAbpXMH8ozOrmu24","slug":"fiona-biohacking-research-query-c3a7e658","name":"Fiona Biohacking Research Query","description":"User Generated App","url":"https://fiona-125b95be.base44.app/functions/biohackingQuery","method":"POST","headers":{},"bodySchema":{"type":"object","required":["question"],"properties":{"question":{"type":"string","description":"Your research question about biohacking, human performance optimization, wearables, supplements, or DIY biology"},"max_results":{"type":"number","description":"Max results to return (default: 10)"}}},"responseSchema":{"type":"object","properties":{"topic":{"type":"string"},"answer":{"type":"string","description":"Synthesized biohacking and human optimization research with citations"},"sources":{"type":"array","items":{"type":"object","properties":{"url":{"type":"string"},"date":{"type":"string"},"title":{"type":"string"},"source":{"type":"string"}}}},"question":{"type":"string"},"timestamp":{"type":"string"},"items_searched":{"type":"number"}}},"example":{"request":{"question":"What are the most effective evidence-based supplements for cognitive performance and mental clarity?","max_results":10},"response":{"topic":"Biohacking","answer":"**Quick Answer**\nDouble-blind crossover trial: exogenous beta-hydroxybutyrate supplementation improves working memory by 18%, reaction time by 12%, and reduces plasma neuroinflammation markers (IL-6, TNF-a) in adults 50+. Effects sustained for 6 hours post-ingestion. Optimal dose: 25g BHB salts.\n\n**Key Findings**\n• **[RESEARCH] Exogenous ketones (BHB) improve cognitive performance and reduce neuroinflammation** (PubMed, 2026-02-05)\n  Double-blind crossover trial: exogenous beta-hydroxybutyrate supplementation improves working memory by 18%, reaction time by 12%, and reduces plasma neuroinflammation markers (IL-...\n  🔗 https://pubmed.ncbi.nlm.nih.gov/?term=exogenous+ketones+BHB+cognitive+neuroinflammation\n\n• **[RESEARCH] Home-based photobiomodulation improves cognitive function in mild cognitive impairment (Alzheimer's): RCT** (PubMed, 2026-04-23)\n  Home-based transcranial photobiomodulation improves cognitive function in mild cognitive impairment due to Alzheimer's disease: A randomized, double-blind, placebo-controlled confi...\n  🔗 https://pubmed.ncbi.nlm.nih.gov/42024020/\n\n• **[RESEARCH] Sleep optimization — 4-7-8 breathing, magnesium glycinate, and CBTI reduce sleep latency** (PubMed, 2026-02-25)\n  Head-to-head trial of sleep interventions: Cognitive Behavioral Therapy for Insomnia (CBTI) reduces sleep latency by 43 minutes vs baseline. Magnesium glycinate (400mg) reduces lat...\n  🔗 https://pubmed.ncbi.nlm.nih.gov/?term=sleep+optimization+magnesium+CBTI+latency+RCT\n\n• **[RESEARCH] Red and near-infrared light therapy (photobiomodulation) improves mitochondrial function** (PubMed, 2026-03-01)\n  Systematic review of 34 RCTs confirms red light (630-670nm) and near-infrared (810-850nm) photobiomodulation increases mitochondrial ATP production by 24%, reduces oxidative stress...\n  🔗 https://pubmed.ncbi.nlm.nih.gov/?term=photobiomodulation+red+light+mitochondria+RCT\n\n**What to Watch Next**\n• Next-gen continuous glucose monitors (CGM 3.0)\n• GLP-1 + biohacking stack combinations\n• AI-powered personalized longevity protocols\n\n---\n*10 sources. Updated 6/12/2026.*","sources":[{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=exogenous+ketones+BHB+cognitive+neuroinflammation","date":"2026-02-05","title":"[RESEARCH] Exogenous ketones (BHB) improve cognitive performance and reduce neuroinflammation","source":"PubMed"},{"url":"https://pubmed.ncbi.nlm.nih.gov/42024020/","date":"2026-04-23","title":"[RESEARCH] Home-based photobiomodulation improves cognitive function in mild cognitive impairment (Alzheimer's): RCT","source":"PubMed"},{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=sleep+optimization+magnesium+CBTI+latency+RCT","date":"2026-02-25","title":"[RESEARCH] Sleep optimization — 4-7-8 breathing, magnesium glycinate, and CBTI reduce sleep latency","source":"PubMed"},{"url":"https://pubmed.ncbi.nlm.nih.gov/?term=photobiomodulation+red+light+mitochondria+RCT","date":"2026-03-01","title":"[RESEARCH] Red and near-infrared light therapy (photobiomodulation) improves mitochondrial function","source":"PubMed"},{"url":"https://news.google.com/search?q=Bryan+Johnson+Blueprint+2026+supplement+stack","date":"2026-04-12","title":"Bryan Johnson's Blueprint stack 2026 update — 111 supplements, biomarker targets, and protocol changes","source":"GoogleNews"}],"question":"What are the most effective evidence-based supplements for cognitive performance and mental clarity?","timestamp":"2026-06-12T04:45:55.357Z","free_trial":true,"items_searched":16}},"exampleRequest":{"question":"What are the most effective evidence-based supplements for cognitive performance and mental clarity?","max_results":10},"tags":["x402"],"displayCostAmount":"1","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$1/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"1","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"1","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_PwS2qUjYBwhzSAEoQ1qPo","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"1","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Answers research questions about biohacking, human performance optimization, wearables, supplements, and DIY biology with synthesized results and citations","exampleAgentPrompt":"Can you research what the current evidence says about berberine as a glucose regulator and longevity compound — give me a synthesized answer with sources, up to 10 results?","exampleUseCases":[{"title":"Evaluate sleep optimization protocols","prompt":"I'm trying to improve my sleep quality. Can you research the latest evidence on sleep stacks—like magnesium, L-theanine, and glycine—and tell me which combinations have the strongest science behind them? Give me a synthesized answer with sources."},{"title":"Compare wearable devices for recovery","prompt":"I want to track my recovery metrics more accurately. Can you research what the current evidence says about the best wearables for HRV, skin temperature, and muscle tension monitoring? Synthesize the findings and give me sources so I can decide which device to invest in."},{"title":"Assess biohacking protocols for longevity","prompt":"I'm interested in extending my healthspan. Can you research what the latest science says about the most effective biohacking practices—like sauna use, fasting windows, and strength training frequency—for longevity and aging? Give me a synthesized answer with up to 15 sources."}],"resultDescription":"Returns a JSON object containing a synthesized answer to the biohacking research question, the topic label, the original question, a timestamp, the number of items searched, and an array of source objects each with a URL, title, date, and source name.","failureModes":["Missing required 'question' field returns a 400-level error","Overly vague or off-topic questions may return low-quality or empty results","Network or upstream research service errors may cause 500-level failures","Payment not completed (x402) results in 402 Payment Required before any result is returned"],"whenToPreferThis":"Choose this endpoint when you need synthesized, cited research answers specifically in the biohacking, human performance, wearables, supplements, or DIY biology space. It aggregates and synthesizes multiple sources rather than returning raw search results, making it ideal when a user needs a coherent answer with citations rather than just a list of links.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-15T12:51:15.531Z","isFirstParty":false}