{"uid":"cap_xpEdz2wKCoTDKkgIX-Rir","slug":"zisman-2002-localized-n0m0-uiss-risk-classifier-rcc-dc9163ee","name":"Zisman 2002 Localized N0M0 UISS Risk Classifier (RCC)","description":"Zisman 2002 localized N0M0 UISS for surgically resected unilateral RCC. Caller-assigned 1997 pathological T (t1-t4), Fuhrman 1-4, ECOG 0-4, and n0_m0 true. Returns low_risk (T1, Fuhrman 1-2, ECOG 0), high_risk (T3 with Fuhrman 2-4 and ECOG ≥1, or any T4), or intermediate_risk (every other N0M0 combination). Not 2001 I-V. Not metastatic UISS. Not SSIGN. magent does not assign TNM or read slides. Not a diagnosis. Not a medical device.","url":"https://api.magentlab.com/api/calc/uiss?utm_source=zero.xyz","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["t_stage","n0_m0","fuhrman_grade","ecog"],"properties":{"ecog":{"type":"integer","description":"Oken 1982 ECOG performance status 0-4 as assigned by the caller. Grade 5 (dead) is not scored. magent does not observe the patient."},"n0_m0":{"type":"boolean","description":"Must be true: surgically resected unilateral RCC that is node-negative and metastasis-negative (Zisman 2002 localized N0M0 UISS). N-positive or M-positive disease is out of scope. Not metastatic UISS."},"t_stage":{"enum":["t1","t2","t3","t4"],"type":"string","description":"1997 pathological T as assigned by the caller (Zisman 2002 localized UISS). t1, t2, t3, or t4. Caller maps T1a/T1b to t1. magent does not assign TNM or read slides."},"fuhrman_grade":{"type":"integer","description":"Fuhrman 1982 nuclear grade 1-4 as assigned by the caller (same parsing as Fuhrman). Integer 1-4 only; reject 0, 5, 1.5, and roman I. magent does not read slides."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_t8oraRfTjtjuq64ZabVKZ","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Stratifies surgically resected, node-negative, metastasis-free unilateral renal cell carcinoma into low, intermediate, or high risk using the Zisman 2002 localized UISS model (pathological T-stage, Fuhrman grade, ECOG)","exampleAgentPrompt":"Using the Zisman 2002 localized UISS model, what's the risk group for a patient with pathological T-stage t3, Fuhrman grade 3, ECOG performance status 1, and confirmed N0M0 disease after surgical resection?","exampleUseCases":[{"title":"Post-nephrectomy risk stratification for surveillance planning","prompt":"I have a patient who just had a nephrectomy for localized RCC — pathological T2, Fuhrman grade 2, ECOG 0, node-negative and no mets confirmed. Can you run the Zisman 2002 UISS to get their risk group?"},{"title":"Oncology dashboard risk classification at scale","prompt":"For our RCC registry dashboard, classify this case using the localized UISS: T-stage t1, Fuhrman grade 1, ECOG 0, N0M0 confirmed — what risk tier does Zisman 2002 assign?"},{"title":"High-risk RCC identification before adjuvant therapy discussion","prompt":"Before the tumor board meeting, can you check whether this patient's RCC falls into the high-risk UISS group? They're T4, Fuhrman grade 4, ECOG 2, surgically resected, N0M0."}],"resultDescription":"Returns one of three risk classifications: low_risk (T1 with Fuhrman grade 1-2 and ECOG 0), high_risk (T3 with Fuhrman 2-4 and ECOG ≥1, or any T4), or intermediate_risk (all other N0M0 combinations meeting the eligibility criteria).","failureModes":["n0_m0 set to false — endpoint is out of scope for node-positive or metastatic disease","fuhrman_grade outside integer range 1-4 (e.g. 0, 5, or non-integer) — rejected","ecog value of 5 (deceased) — not scored, rejected","t_stage not one of t1/t2/t3/t4 — enum validation failure","metastatic UISS or 2001 I-V staging requested — wrong endpoint","missing required query parameters — request rejected"],"whenToPreferThis":"Use this endpoint when you need the Zisman 2002 localized (N0M0) UISS risk group specifically — i.e. the three-tier stratification (low/intermediate/high) for surgically resected, node-negative, metastasis-free unilateral RCC using 1997 pathological T-stage, Fuhrman grade 1-4, and ECOG 0-4. Do not use for metastatic UISS, 2001 Roman-numeral I-V staging, SSIGN score, or any case where N or M status is positive. Prefer this over manual lookup tables when integrating risk stratification into clinical workflows or oncology dashboards.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-10-16T06:55:01.741Z","isFirstParty":false,"canonicalSlug":"zisman-2002-localized-n0m0-uiss-risk-classifier-rcc-dc9163ee"}