{"uid":"cap_xOAjyl5bQOVOkF2yE8cRK","slug":"drug-safety-fda-brief-6285423d","name":"Drug Safety & FDA Brief","description":"Pay-per-call data and tools for AI agents, $0.002-0.01 per call in USDC via x402 (Base, Polygon or Solana), no account or API key; MAX tiers ($0.05-0.25) run deeper jobs. Agent toolkit: web search, search + read top pages, any page as clean markdown with a prompt-injection check, which-x402-API-to-call recommender, seller check. Data: Google Maps places with contacts, YouTube video data and transcripts, job listings (Indeed, LinkedIn, 13 boards), Google Ads Transparency, TikTok comments, Pinterest, Airbnb, Redfin, AliExpress, app stores, live sports, website and SEO checks, Shopify store tech stacks, and onchain token / address risk checks.","url":"https://agent-data.centorprat.workers.dev/tools/drug-safety-fda-brief?utm_source=zero.xyz","method":"POST","headers":{},"bodySchema":{"type":"object","properties":{"drugs":{"type":"array","items":{"type":"string"},"maxItems":2,"description":"Drugs to brief, e.g. [\"ozempic\"], [\"semaglutide\", \"aspirin\"]. Brand or generic names both work. One brief per drug."}}},"responseSchema":{"type":"json","example":{"items":[{"drug":"ozempic","note":"FAERS adverse-event reports are voluntary and do NOT establish that the drug caused the event; counts reflect reporting, not incidence or causation. Verify against the FDA label and source before any clinical or investment decision.","found":true,"label":{"labelFound":true,"hasBoxedWarning":true,"boxedWarningExcerpt":"WARNING: RISK OF THYROID C-CELL TUMORS • In rodents, semaglutide causes dose-dependent and treatment-duration-dependent thyroid C-cell tumors at clinically relevant exposures. It is unknown whether RYBELSUS and OZEMPIC tablets cause thyroid C-cell tumors, including medullary thyroid carcinoma (MTC),"},"source":"openFDA (api.fda.gov): drugsfda, event (FAERS), enforcement, label","recalls":{"total":1,"recent":[{"date":"2021-03-15","firm":"Cardinal Health Inc.","reason":"CGMP Deviations: Intermittent exposure to temperature excursion during storage.","status":"Terminated","classification":"Class II"}]},"approval":{"routes":["ORAL"],"sponsors":["NOVO"],"matchedBy":"openfda.brand_name","brandNames":["OZEMPIC","RYBELSUS"],"dosageForms":["TABLET"],"applications":["NDA213051"],"genericNames":["ORAL SEMAGLUTIDE"],"marketingStatus":["Prescription"]},"capturedAt":"2026-10-23T11:32:18+00:00","adverseEvents":{"matchedBy":"patient.drug.medicinalproduct","deathReports":1114,"topReactions":[{"count":9751,"reaction":"Nausea"},{"count":6949,"reaction":"Off Label Use"},{"count":6341,"reaction":"Vomiting"},{"count":5980,"reaction":"Diarrhoea"},{"count":4507,"reaction":"Decreased Appetite"},{"count":4406,"reaction":"Constipation"},{"count":4157,"reaction":"Weight Decreased"},{"count":3431,"reaction":"Impaired Gastric Emptying"},{"count":3294,"reaction":"Product Use In Unapproved Indication"},{"count":2962,"reaction":"Blood Glucose Increased"}],"totalReports":66161,"seriousReports":32483}}]}},"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.03","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.03/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.03","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.03","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_clWRy30FTbHf7sQulW-Bb","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.03","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Fuses four openFDA data sources (approvals, FAERS adverse events, recalls, and boxed warnings) into a single composed safety brief for up to two drugs per call","exampleAgentPrompt":"Pull me a full FDA safety brief for ozempic — I want the approval status, top FAERS adverse reactions, any recalls, and whether there's a boxed warning.","exampleUseCases":[{"title":"Pre-prescribing safety check","prompt":"Before I discuss this medication with my doctor, can you pull the full FDA safety brief for eliquis — approvals, adverse events from FAERS, any recalls, and boxed warnings?"},{"title":"Comparing two drug safety profiles","prompt":"I want to compare the FDA safety profiles of warfarin and apixaban side by side — get me the FAERS adverse event counts, serious reactions, deaths, recalls, and any black box warnings for both."},{"title":"Consumer drug safety research","prompt":"My family member was just prescribed adderall and I'm concerned — can you look up its FDA safety record including reported deaths, top adverse reactions in FAERS, recalls, and whether it has a boxed warning?"}],"resultDescription":"A structured safety brief per drug containing: FDA approval status, total FAERS adverse event reports, top reported reactions, count of serious events, count of deaths, active recall information, and full boxed warning text if present. Failed lookups are indicated but not charged.","failureModes":["Drug name not found in any openFDA source — lookup fails gracefully with an error indicator for that drug","More than 2 drugs submitted — rejected by input schema (maxItems: 2)","openFDA upstream API timeout or unavailability — may return partial or error response","Misspelled or highly obscure drug names may yield no results"],"whenToPreferThis":"Use this endpoint when you need a comprehensive, multi-source FDA safety snapshot for one or two drugs in a single call. It is preferred over querying openFDA directly because it fuses four data sources (approvals, FAERS, recalls, boxed warnings) into one response without requiring an API key. Ideal for pre-prescribing research, patient safety checks, or regulatory due diligence workflows where speed and completeness matter more than raw data access.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-10-29T12:37:50.706Z","isFirstParty":false,"canonicalSlug":"drug-safety-fda-brief-6285423d"}