{"uid":"cap_vndH07QtAsfmx82L0BWA0","slug":"ncbi-clinvar-variant-search-via-e-utilities-3d469d4f","name":"NCBI ClinVar Variant Search via E-utilities","description":"Search NCBI ClinVar clinical variants and return matching UIDs for query {q} via E-utilities. Query: ?q= Returns JSON.","url":"https://clonecho.builda.company/x402/s/ncbi-esearch-clinvar","method":"POST","headers":{},"bodySchema":null,"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.02","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"registry","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.02/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.02","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.02","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_wyw_KEnkbVjtCi9LAZ0tG","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.02","costPer":"request","priority":0,"asset":"0x036CbD53842c5426634e7929541eC2318f3dCF7e","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Searches NCBI ClinVar database for clinical genetic variants matching a query and returns matching UIDs via E-utilities esearch.","exampleAgentPrompt":"Can you search ClinVar for pathogenic variants associated with BRCA2 and give me the matching UIDs?","exampleUseCases":null,"resultDescription":"A JSON response containing matching ClinVar UIDs (record identifiers) for the given query, along with metadata such as the total count of results, returned from NCBI E-utilities esearch endpoint.","failureModes":["Empty result set if query matches no ClinVar records","Malformed or missing q parameter returns error","NCBI E-utilities rate limiting or temporary unavailability","Very broad queries may return truncated or paginated UID lists","Special characters in query string may need URL encoding"],"whenToPreferThis":"Use this endpoint when you need to programmatically search NCBI ClinVar for clinical variant records and retrieve their UIDs, especially as the first step in a pipeline to fetch full variant details via NCBI E-utilities. Prefer this over manual ClinVar web searches when integrating genomic/clinical data lookups into automated workflows.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-15T07:01:57.687Z","isFirstParty":false}