{"uid":"cap_tJzkMEtnbKoVOGI_BHYzl","slug":"reactome-biological-pathways-lookup-by-gene-888fcd2b","name":"Reactome Biological Pathways Lookup by Gene","description":"Biological Pathways for a Gene (Reactome). Biological pathways a gene or protein takes part in (Reactome), by gene symbol or UniProt accession: every pathway with its Reactome id, name, disease flag and link. Human by default, ?organism= taxon for others. Reactome, CC BY 4.0.","url":"https://saylorinnovations.com/api/bio/pathways/:id?utm_source=zero.xyz","method":"GET","headers":{},"bodySchema":null,"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.002","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"registry","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.002/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.002","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.002","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_EiZl1gkBN8QsEddml4SdJ","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.002","costPer":"request","priority":0,"asset":null,"unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Returns all Reactome biological pathways associated with a given gene symbol or UniProt accession, including pathway IDs, names, disease flags, and links.","exampleAgentPrompt":"What biological pathways is the gene TP53 involved in according to Reactome? Include any disease-flagged pathways and their Reactome IDs.","exampleUseCases":[{"title":"Cancer gene pathway profiling","prompt":"I'm researching BRCA2 and need to know every Reactome pathway it participates in — especially any flagged as disease-related. Can you pull all the pathway names and IDs?"},{"title":"Drug target pathway context","prompt":"Look up all Reactome pathways for EGFR so I can understand what signaling networks a drug targeting that gene would affect."},{"title":"Mouse model pathway mapping","prompt":"Can you get the Reactome pathways for the Trp53 gene in mouse — use taxon ID 10090 — and list all the pathway names and their Reactome IDs?"}],"resultDescription":"A list of pathways the gene or protein participates in, each including a Reactome pathway ID, human-readable pathway name, a boolean disease flag indicating whether the pathway is disease-associated, a direct Reactome link, and organism context.","failureModes":["Unknown gene symbol or UniProt accession returns empty results or 404","Invalid organism taxon ID returns error or defaults to human unexpectedly","Network timeout for genes involved in very large numbers of pathways","Ambiguous gene symbols that map to multiple genes may return merged or incorrect results","Non-human organism with limited Reactome coverage may return sparse results"],"whenToPreferThis":"Use this endpoint when you need structured Reactome pathway annotations for a specific gene or protein, including disease pathway flags and direct Reactome links. Prefer this over manual Reactome web queries when automating bioinformatics pipelines, enrichment analyses, or building gene-pathway knowledge graphs. It is especially useful for agents needing machine-readable pathway data with UniProt or gene symbol input without requiring direct Reactome API integration.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-10-01T12:51:32.640Z","isFirstParty":false,"canonicalSlug":"reactome-biological-pathways-lookup-by-gene-888fcd2b"}