{"uid":"cap_sMFZk6Y_BhlojEvmi-7qS","slug":"nigrovic-2002-bacterial-meningitis-score-bms-calculator-5d42aeb4","name":"Nigrovic 2002 Bacterial Meningitis Score (BMS) Calculator","description":"Nigrovic 2002 Bacterial Meningitis Score: CSF Gram stain (2), CSF ANC ≥1000 cells/µL (1), CSF protein ≥80 mg/dL (1), peripheral ANC ≥10 000 cells/µL (1), seizure (1). Max 6. very_low_risk if 0, not_low_risk if ≥1. Children with CSF pleocytosis as in Nigrovic 2002; not a neonatal score. Not a meningitis diagnosis or an antibiotic/LP order. magent does not stain CSF, count neutrophils, assay protein, or witness a seizure.","url":"https://api.magentlab.com/api/calc/bacterial_meningitis","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["csf_gram_stain","csf_anc_ge_1000","csf_protein_ge_80","peripheral_anc_ge_10000","seizure"],"properties":{"seizure":{"type":"boolean","description":"Seizure at or before presentation as assigned by the caller (Nigrovic 2002). true scores 1. magent does not witness a seizure."},"csf_gram_stain":{"type":"boolean","description":"Positive CSF Gram stain as assigned by the caller (Nigrovic 2002). true scores 2, not 1. magent does not stain CSF."},"csf_anc_ge_1000":{"type":"boolean","description":"CSF ANC ≥1000 cells/µL as assigned by the caller (Nigrovic 2002). true scores 1. magent does not count neutrophils."},"csf_protein_ge_80":{"type":"boolean","description":"CSF protein ≥80 mg/dL as assigned by the caller (Nigrovic 2002). true scores 1. magent does not assay protein."},"peripheral_anc_ge_10000":{"type":"boolean","description":"Peripheral ANC ≥10 000 cells/µL as assigned by the caller (Nigrovic 2002). true scores 1. magent does not count neutrophils."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":{"type":"json","example":{"path":"/api/calc/bacterial_meningitis","count":2,"items":[{"score":0,"formula":"bacterial_meningitis","citation":{"id":"nigrovic-2002","doi":"10.1542/peds.110.4.712","pmid":"12359784","title":"Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era","source":"Pediatrics. 2002;110(4):712-719","authors":"Nigrovic LE, Kuppermann N, Malley R"},"max_score":6,"components":[{"factor":"csf_gram_stain","points":0,"present":false},{"factor":"csf_anc_ge_1000","points":0,"present":false},{"factor":"csf_protein_ge_80","points":0,"present":false},{"factor":"peripheral_anc_ge_10000","points":0,"present":false},{"factor":"seizure","points":0,"present":false}],"disclaimer":"Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.","formula_expression":"Bacterial Meningitis Score = csf_gram_stain 2 + csf_anc_ge_1000 1 + csf_protein_ge_80 1 + peripheral_anc_ge_10000 1 + seizure 1; Nigrovic 2002; max 6; very_low_risk 0, not_low_risk ≥1","bacterial_meningitis_band":"very_low_risk"},{"score":0,"formula":"bacterial_meningitis","citation":{"id":"nigrovic-2002","doi":"10.1542/peds.110.4.712","pmid":"12359784","title":"Development and validation of a multivariable predictive model to distinguish bacterial from aseptic meningitis in children in the post-Haemophilus influenzae era","source":"Pediatrics. 2002;110(4):712-719","authors":"Nigrovic LE, Kuppermann N, Malley R"},"max_score":6,"components":[{"factor":"csf_gram_stain","points":0,"present":false},{"factor":"csf_anc_ge_1000","points":0,"present":false},{"factor":"csf_protein_ge_80","points":0,"present":false},{"factor":"peripheral_anc_ge_10000","points":0,"present":false},{"factor":"seizure","points":0,"present":false}],"disclaimer":"Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.","formula_expression":"Bacterial Meningitis Score = csf_gram_stain 2 + csf_anc_ge_1000 1 + csf_protein_ge_80 1 + peripheral_anc_ge_10000 1 + seizure 1; Nigrovic 2002; max 6; very_low_risk 0, not_low_risk ≥1","bacterial_meningitis_band":"very_low_risk"}]}},"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_CX_JPZ3IPie9m8h2INcmi","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Computes the Nigrovic 2002 Bacterial Meningitis Score from five clinical boolean flags and returns a risk classification (very_low_risk if 0, not_low_risk if ≥1) with a maximum score of 6.","exampleAgentPrompt":"Score this pediatric meningitis case using the Nigrovic 2002 Bacterial Meningitis Score: CSF Gram stain is negative, CSF ANC is above 1000 cells/µL (true), CSF protein is below 80 mg/dL (false), peripheral ANC is above 10,000 cells/µL (true), and the child had a seizure at presentation (true).","exampleUseCases":[{"title":"Pediatric ED meningitis risk stratification","prompt":"I have a child in the ED with CSF pleocytosis. Gram stain is negative, CSF ANC is over 1000 (true), CSF protein is under 80 (false), peripheral ANC is under 10,000 (false), and no seizure. Can you calculate the Nigrovic Bacterial Meningitis Score and tell me if they're very low risk?"},{"title":"Clinical decision support for hospitalist","prompt":"Run the 2002 Nigrovic Bacterial Meningitis Score for this patient — CSF Gram stain positive (true), CSF ANC over 1000 (true), CSF protein over 80 mg/dL (true), peripheral ANC over 10,000 (true), seizure at presentation (true). What's the total score and risk category?"},{"title":"Retrospective chart audit scoring","prompt":"For a retrospective audit, calculate the Bacterial Meningitis Score for a case where Gram stain was negative, CSF ANC was under 1000 (false), protein under 80 (false), peripheral ANC under 10,000 (false), and no seizure — is this a very low risk score?"}],"resultDescription":"Returns the total Bacterial Meningitis Score (0–6), where a positive CSF Gram stain contributes 2 points and each other positive criterion (CSF ANC ≥1000, CSF protein ≥80, peripheral ANC ≥10,000, seizure) contributes 1 point. Also returns a risk classification: 'very_low_risk' if the total score is 0, or 'not_low_risk' if the score is ≥1.","failureModes":["Missing required boolean query parameters (csf_gram_stain, csf_anc_ge_1000, csf_protein_ge_80, peripheral_anc_ge_10000, seizure) returns a validation error","Passing non-boolean values for boolean fields causes a schema validation failure","Score applies only to children with CSF pleocytosis; caller must ensure patient population is appropriate (not neonates)","No network connectivity or payment failure via x402 results in no response"],"whenToPreferThis":"Use this endpoint when you need to apply the validated Nigrovic 2002 Bacterial Meningitis Score to a pediatric patient with CSF pleocytosis and already have the five required clinical data points (Gram stain result, CSF ANC threshold, CSF protein threshold, peripheral ANC threshold, seizure status). Prefer this over general LLM reasoning when you need an auditable, deterministic score. Do not use for neonates or as a standalone meningitis diagnosis tool.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-15T07:10:27.173Z","isFirstParty":false}