{"uid":"cap_rFJbiq44EEnQ6eCUWurDn","slug":"acr-eular-2016-primary-sj-gren-s-syndrome-classification-score-a8353584","name":"ACR/EULAR 2016 Primary Sjögren's Syndrome Classification Score (Shiboski Table 3)","description":"ACR/EULAR 2016 primary Sjögren classification (Shiboski Table 3). Required: inclusion_met true (AECG dryness or ESSDAI domain) and exclusion_present false (no radiation, HCV, AIDS, sarcoid, amyloid, GVHD, IgG4-RD). Score: labial biopsy FS ≥1 3, anti-SSA/Ro 3, ocular staining 1, Schirmer 1, UWS 1; max 9; classified iff ≥4. Not a diagnosis. Not AECG 2002. Not 2012 ACR-only. magent does not stain eyes, measure saliva, or read biopsies.","url":"https://api.magentlab.com/api/calc/acr_eular_sjogren","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["inclusion_met","exclusion_present","labial_biopsy_fs_ge_1","anti_ssa_ro","ocular_staining","schirmer","uws"],"properties":{"uws":{"type":"boolean","description":"Unstimulated whole saliva flow rate ≤0.1 ml/minute (Shiboski 2016 Table 3). true scores 1; false scores 0. magent does not measure saliva."},"schirmer":{"type":"boolean","description":"Schirmer's test ≤5 mm/5 minutes in at least one eye (Shiboski 2016 Table 3). true scores 1; false scores 0. magent does not perform Schirmer testing."},"anti_ssa_ro":{"type":"boolean","description":"Anti-SSA/Ro positive as assigned by the caller (Shiboski 2016 Table 3). true scores 3; false scores 0. Anti-SSB/La without SSA is not an item. magent does not assay autoantibodies."},"inclusion_met":{"type":"boolean","description":"Must be true. Shiboski 2016 inclusion as assigned by the caller: at least one AECG ocular or oral dryness question positive, or suspicion of Sjögren's syndrome from ESSDAI with at least one positive domain item. false is invalid and is not scored. magent does not take a dryness history."},"ocular_staining":{"type":"boolean","description":"Ocular staining score ≥5 or van Bijsterveld ≥4 in at least one eye (Shiboski 2016 Table 3). true scores 1; false scores 0. magent does not stain eyes."},"exclusion_present":{"type":"boolean","description":"Must be false. Shiboski 2016 exclusion as assigned by the caller: none of head and neck radiation, active HCV with PCR confirmation, AIDS, sarcoidosis, amyloidosis, graft-versus-host disease, or IgG4-related disease. true is invalid and is not scored. magent does not diagnose exclusion conditions."},"labial_biopsy_fs_ge_1":{"type":"boolean","description":"Labial salivary gland with focal lymphocytic sialadenitis and focus score ≥1 foci/4 mm² (Shiboski 2016 Table 3). true scores 3; false scores 0. magent does not read biopsies."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_UlP8eRZNYPIUjWlbpHM87","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Computes the ACR/EULAR 2016 Sjögren's syndrome classification score from five weighted clinical items and returns whether the patient meets the ≥4 threshold for classification.","exampleAgentPrompt":"Score this patient under the ACR/EULAR 2016 primary Sjögren's classification: inclusion is met, no exclusions apply, labial biopsy focus score is ≥1, anti-SSA/Ro is positive, ocular staining is positive, Schirmer's test is negative, and UWS is negative — what's the total score and does the patient classify?","exampleUseCases":[{"title":"Rheumatology clinic Sjögren workup","prompt":"I have a patient with confirmed AECG dryness (inclusion met), no exclusionary conditions, a labial biopsy focus score of 1, anti-SSA/Ro positive, ocular staining score of 5 in one eye, Schirmer's borderline at 6 mm so negative, and UWS negative — can you run the ACR/EULAR 2016 Sjogren score and tell me if they classify?"},{"title":"Research cohort eligibility screening","prompt":"For our Sjögren's research cohort I need to screen this participant: inclusion criterion met via ESSDAI, no exclusions present, biopsy focus score ≥1, anti-SSA/Ro negative, no abnormal ocular staining, Schirmer's positive, UWS positive — what's the 2016 ACR/EULAR score and do they hit the threshold of 4?"},{"title":"Telemedicine second-opinion scoring","prompt":"Can you apply the 2016 Shiboski ACR/EULAR Sjögren classification criteria to this remote patient: inclusion met, exclusions absent, labial biopsy positive (FS ≥1), anti-SSA/Ro positive, ocular staining negative, Schirmer's negative, UWS negative — give me the score out of 9 and whether they're classified."}],"resultDescription":"Returns the numeric total score (0–9) computed from the five weighted items (labial biopsy FS ≥1 = 3 pts, anti-SSA/Ro = 3 pts, ocular staining = 1 pt, Schirmer's = 1 pt, UWS = 1 pt), plus a boolean classification result indicating whether the score is ≥4 (meeting ACR/EULAR 2016 classification threshold). The endpoint does not return a diagnosis; it returns a classification score only.","failureModes":["inclusion_met=false: invalid input, request rejected or unscored — caller must ensure at least one AECG dryness criterion or positive ESSDAI domain","exclusion_present=true: invalid input, request rejected or unscored — caller must confirm absence of all listed exclusions before submitting","Missing required query parameters: 400-level error if any of the seven required fields are absent","Boolean type mismatch: passing strings instead of booleans may cause schema validation errors","Score of 0–3: patient does not classify; this is not an error but agents must not interpret it as a diagnosis of exclusion"],"whenToPreferThis":"Use this endpoint when you need to apply the specific ACR/EULAR 2016 (Shiboski Table 3) Sjögren's classification algorithm — not the older 2002 AECG criteria or the 2012 ACR-only criteria. All five clinical test results (biopsy, serology, ocular staining, Schirmer's, UWS) must already be determined by the caller from laboratory and clinical sources; this endpoint only performs the scoring arithmetic and threshold check. Prefer it over manual calculation to avoid arithmetic errors and to ensure the correct item weights (3/3/1/1/1) are applied consistently.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-13T13:01:19.243Z","isFirstParty":false}