{"uid":"cap_nK--nll1oqtMTJP60ELi4","slug":"impede-vte-risk-score-calculator-for-multiple-myeloma-e9caa0c3","name":"IMPEDE VTE Risk Score Calculator for Multiple Myeloma","description":"Sanfilippo 2019 IMPEDE VTE for multiple myeloma: IMiD 4, BMI>=25 1, pelvic/hip/femur fracture 4, ESA 1, doxorubicin 3, dexamethasone none/low/high 0/2/4 (high if monthly >160 mg), Asian/Pacific Islander -3 (caller-assigned), VTE history 5, tunneled line 2, thromboprophylaxis none/prophylactic/therapeutic 0/-3/-4. Unclamped. <=3 low 3.3%, 4-7 intermediate 8.3%, >=8 high 15.2%. Not a prophylaxis order. Not SAVED or Khorana.","url":"https://api.magentlab.com/api/calc/impede_vte","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["imid","bmi_ge_25","pelvic_hip_femur_fracture","esa","doxorubicin","dexamethasone","asian_pacific_islander","vte_history","tunneled_line","thromboprophylaxis"],"properties":{"esa":{"type":"boolean","description":"Erythropoiesis-stimulating agent as assigned by the caller (Sanfilippo 2019 Table 3). true or false. 1 point if true."},"imid":{"type":"boolean","description":"Immunomodulatory drug (IMiD) as assigned by the caller (Sanfilippo 2019 Table 3). true or false. 4 points if true."},"bmi_ge_25":{"type":"boolean","description":"BMI ≥25 kg/m2 as assigned by the caller (Sanfilippo 2019 Table 3). true or false. magent does not compute BMI from height or weight. 1 point if true."},"doxorubicin":{"type":"boolean","description":"Doxorubicin as assigned by the caller (Sanfilippo 2019 Table 3). true or false. 3 points if true."},"vte_history":{"type":"boolean","description":"History of VTE before multiple myeloma as assigned by the caller (Sanfilippo 2019 Table 3). true or false. 5 points if true."},"dexamethasone":{"enum":["none","low","high"],"type":"string","description":"Dexamethasone as assigned by the caller (Sanfilippo 2019 Table 3). none (not on dexamethasone) scores 0; low (dexamethasone used at total monthly dosing ≤160 mg) scores 2; high (total monthly dosing >160 mg) scores 4. Not the NCCN ≥480 mg definition."},"tunneled_line":{"type":"boolean","description":"Tunneled line / central venous catheter as assigned by the caller (Sanfilippo 2019 Table 3). true or false. 2 points if true."},"thromboprophylaxis":{"enum":["none","prophylactic","therapeutic"],"type":"string","description":"Existing thromboprophylaxis as assigned by the caller (Sanfilippo 2019 Table 3). Mutually exclusive. none scores 0; prophylactic (prophylactic LMWH or aspirin) scores −3; therapeutic (therapeutic LMWH or warfarin) scores −4."},"asian_pacific_islander":{"type":"boolean","description":"Caller-assigned ethnicity/race Asian/Pacific Islander as used in Sanfilippo 2019. true or false. magent does not assign race or ethnicity. −3 if true."},"pelvic_hip_femur_fracture":{"type":"boolean","description":"Pelvic, hip, or femur fracture as assigned by the caller (Sanfilippo 2019 Table 3). true or false. 4 points if true."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_elpg9KT587BEWHebhOs2f","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Calculates the Sanfilippo 2019 IMPEDE VTE risk score for venous thromboembolism in multiple myeloma patients, returning a numeric score and risk category (low/intermediate/high).","exampleAgentPrompt":"My multiple myeloma patient is on an IMiD, has a BMI over 25, no pelvic fracture, is not on ESA, is on doxorubicin, is on high-dose dexamethasone (over 160 mg/month), is not Asian or Pacific Islander, has no prior VTE, has a tunneled line, and is on no thromboprophylaxis — what's their IMPEDE VTE risk score and category?","exampleUseCases":[{"title":"New myeloma patient VTE triage","prompt":"I have a newly diagnosed myeloma patient starting lenalidomide (IMiD), BMI is 28, no fracture, not on ESA, not on doxorubicin, on low-dose dexamethasone (≤160 mg/month), not Asian/Pacific Islander, no VTE history, no tunneled line, and on prophylactic anticoagulation — what does the IMPEDE score come out to and what risk tier are they in?"},{"title":"High-risk treatment regimen assessment","prompt":"Can you calculate the IMPEDE VTE score for a myeloma patient who is on an IMiD, has BMI over 25, had a pelvic fracture, is on ESA, is on doxorubicin, is on high dexamethasone, is not Asian or Pacific Islander, has a prior VTE, has a tunneled central line, and is currently on no thromboprophylaxis?"},{"title":"De-escalation decision for low-risk patient","prompt":"Run the Sanfilippo IMPEDE VTE model for a myeloma patient not on IMiD, BMI under 25, no fracture, no ESA, no doxorubicin, no dexamethasone, is Asian/Pacific Islander, no VTE history, no tunneled line, and currently on therapeutic anticoagulation — I want to see if the score supports de-escalation."}],"resultDescription":"Returns a computed IMPEDE VTE total score (integer), a risk category label (low ≤3, intermediate 4–7, high ≥8), and the associated empirical VTE probability (low 3.3%, intermediate 8.3%, high 15.2%) based on Sanfilippo 2019 Table 3 factor weights.","failureModes":["Missing required query parameter returns an error (all 10 factors are required)","Invalid enum value for dexamethasone or thromboprophylaxis returns a validation error","Boolean fields passed as strings instead of true/false may cause parsing errors","Score is not a prophylaxis recommendation and should not be used as one","Caller-assigned flags (e.g. Asian/Pacific Islander, IMiD) may introduce scoring bias if incorrectly assigned"],"whenToPreferThis":"Use this endpoint when you need to calculate the Sanfilippo 2019 IMPEDE VTE risk score specifically for multiple myeloma patients. Prefer it over Khorana or SAVED score calculators when the patient has myeloma-specific risk factors like IMiD use, dexamethasone dosing, or Asian/Pacific Islander identity modifier. This endpoint uses the IMPEDE model only — it does not compute Khorana, SAVED, or general surgical VTE scores.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-15T13:05:38.597Z","isFirstParty":false}