{"uid":"cap_lin7N49mg-xyj0K5l46Fo","slug":"gtex-gene-expression-lookup-b0af631a","name":"GTEx Gene Expression Lookup","description":"GTEx Portal gene expression (public API v2, no key): median TPM of one gene in human tissues, sorted highest first, with the GENCODE id it was matched to. Uses GTEx v8 data; unknown gene symbols return 404.","url":"https://api.webintel-api.workers.dev/api/search/gtex-gene-expression?utm_source=zero.xyz","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET"],"type":"string"},"queryParams":{"type":"object","required":["gene"],"properties":{"gene":{"type":"string","description":"Gene symbol such as BRCA1 (letters, digits and dash, up to 20 characters)"},"limit":{"type":"string","description":"How many tissues, 1 to 54 (default 10)"}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.002","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.002/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.002","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.002","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_ykVCDY3sFsuQD3XTXPvtc","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.002","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Returns median TPM expression levels for a human gene across all GTEx v8 tissues, sorted highest to lowest, with the matched GENCODE ID.","exampleAgentPrompt":"Can you look up where BRCA1 is most highly expressed in human tissues using GTEx data, and show me the top 15 tissues by median TPM?","exampleUseCases":[{"title":"Tissue specificity for drug target","prompt":"I'm researching EGFR as a drug target — can you pull the top 20 tissues where it's most expressed in GTEx v8 and show me the median TPM values?"},{"title":"Cancer gene expression profiling","prompt":"Can you get me the GTEx median TPM expression for TP53 across all available tissues, sorted from highest to lowest?"},{"title":"Housekeeping gene verification","prompt":"I want to confirm GAPDH is expressed broadly — can you look it up in GTEx and show me the top 10 tissues by median TPM along with its GENCODE ID?"}],"resultDescription":"A ranked list of human tissues with their median TPM values for the queried gene, ordered from highest to lowest expression, along with the GENCODE gene ID that was matched. Returns up to 54 tissues (default 10). Returns 404 if the gene symbol is not recognized in GTEx v8.","failureModes":["Unknown gene symbol returns 404 — only gene symbols present in GTEx v8 are supported","Invalid limit parameter (outside 1–54 range) may cause an error or be clamped","Misspelled gene symbols are not fuzzy-matched and will fail","Gene aliases not recognized by GTEx v8 GENCODE mapping will not resolve"],"whenToPreferThis":"Use this endpoint when you need median TPM gene expression data across human tissues from the GTEx v8 dataset. It is ideal for bioinformatics pipelines, drug target research, or any scenario requiring authoritative human tissue expression rankings for a known HGNC gene symbol. Prefer this over manual GTEx Portal browsing when you need programmatic, structured expression data with GENCODE IDs.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-10-25T12:31:24.547Z","isFirstParty":false,"canonicalSlug":"gtex-gene-expression-lookup-b0af631a"}