{"uid":"cap_iUT4sDOtThm26osqcoWmH","slug":"rhd-immune-globulin-vial-arithmetic-acog-pb-181-aabb-a8851a56","name":"RhD Immune Globulin Vial Arithmetic (ACOG PB 181 / AABB)","description":"ACOG Practice Bulletin 181 RhD immune globulin vial arithmetic. fmh_ml = fetal_cells_percent/100 * maternal_blood_volume_ml. One 300 microgram vial covers 30 mL Rh D-positive fetal whole blood. AABB Technical Manual rounding: if frac(fmh_ml/30) >= 0.5 round up then add one vial; if < 0.5 round down then add one. Minimum 1 vial. Caller assigns Kleihauer–Betke percent and maternal volume; magent does not read slides. Not a prescription or brand order.","url":"https://api.magentlab.com/api/calc/rhig","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["fetal_cells_percent","maternal_blood_volume_ml"],"properties":{"fetal_cells_percent":{"type":"number","description":"Caller-assigned Kleihauer–Betke fetal-cell percent (0-5). magent does not interpret slides."},"maternal_blood_volume_ml":{"type":"number","description":"Caller-assigned maternal blood volume in mL (3000-10000). magent does not compute Nadler EBV."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_l9mHMA0Q9-S9_hFxB1Yrl","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Calculates the number of RhD immune globulin (RhIG) vials required after fetomaternal hemorrhage using the Kleihauer–Betke percent and maternal blood volume, following ACOG Practice Bulletin 181 and AABB Technical Manual rounding rules.","exampleAgentPrompt":"My patient has a Kleihauer-Betke result of 0.8% fetal cells and an estimated maternal blood volume of 5000 mL — how many 300-microgram RhIG vials does she need per ACOG and AABB guidelines?","exampleUseCases":[{"title":"Post-trauma RhIG dosing after large hemorrhage","prompt":"A Rh-negative trauma patient had a Kleihauer-Betke of 2.1% and her maternal blood volume is estimated at 6500 mL — how many RhIG vials does she need?"},{"title":"Routine third-trimester antepartum prophylaxis check","prompt":"My Rh-negative patient at 28 weeks had a KB of 0.1% with a maternal volume of 4200 mL, can you calculate how many RhIG vials are required per ACOG PB 181?"},{"title":"Large FMH dosing after abruption","prompt":"We had a significant abruption and the KB came back at 4.5% fetal cells; maternal blood volume is 8000 mL — run the AABB vial rounding calculation for RhIG."}],"resultDescription":"Returns the calculated fetomaternal hemorrhage volume in mL (fmh_ml = fetal_cells_percent/100 × maternal_blood_volume_ml), the fractional vial count before rounding, and the final integer number of RhIG vials required per AABB Technical Manual rounding rules (minimum 1 vial). Does not issue a prescription or specify a brand.","failureModes":["fetal_cells_percent outside 0–5 range returns a validation error","maternal_blood_volume_ml outside 3000–10000 range returns a validation error","missing required query parameters returns a 400 error","payment not included or insufficient returns a 402 Payment Required"],"whenToPreferThis":"Use this endpoint when you need a fast, guideline-anchored RhIG vial count from a Kleihauer–Betke result and maternal blood volume, specifically implementing ACOG Practice Bulletin 181 arithmetic and AABB Technical Manual rounding. Prefer it over manual calculation to avoid rounding errors in high-stakes obstetric or trauma transfusion scenarios.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T13:05:20.420Z","isFirstParty":false}