{"uid":"cap_hD2AVgXXbgDbtkfvx3W66","slug":"hiet-dosing-calculator-engebretsen-2011-03d8669e","name":"HIET Dosing Calculator (Engebretsen 2011)","description":"High-dose insulin euglycemia therapy (HIET) from Engebretsen 2011: 1 U/kg insulin bolus, then a 1-10 U/kg/h continuous infusion. Weight in kg or lb. Not a prescription. Used in beta-blocker or calcium-channel-blocker cardiogenic shock. magent does not titrate, choose dextrose, or add DigiFab, glucagon, or calcium. Deterministic published arithmetic with citation.","url":"https://api.magentlab.com/api/calc/hiet","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":[],"properties":{"weight_kg":{"type":"number","description":"Weight in kilograms (1-500). Provide weight_kg or weight_lb."},"weight_lb":{"type":"number","description":"Weight in pounds (2-1100). Converted as kg = lb * 0.45359237."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_2myBB5w8PwB6muv_Je-j0","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Calculates insulin bolus and infusion doses for high-dose insulin euglycemia therapy (HIET) in beta-blocker or calcium-channel-blocker cardiogenic shock based on patient weight","exampleAgentPrompt":"Calculate the HIET insulin bolus and infusion dose for a patient weighing 85 kg who is in cardiogenic shock from a calcium-channel-blocker overdose using the Engebretsen 2011 protocol.","exampleUseCases":[{"title":"CCB overdose emergency dosing","prompt":"My patient just came in with severe cardiogenic shock after a calcium-channel-blocker overdose and weighs 75 kg — what's the insulin bolus and infusion range for HIET?"},{"title":"Beta-blocker toxicity in pediatric patient","prompt":"I have a pediatric patient in beta-blocker-induced cardiogenic shock weighing 40 kg — calculate the HIET insulin dose using the Engebretsen protocol."},{"title":"Weight in pounds HIET conversion","prompt":"For a 220-pound patient needing high-dose insulin euglycemia therapy for CCB toxicity, what should the insulin bolus and infusion rate be?"}],"resultDescription":"Returns the calculated 1 U/kg insulin bolus dose and the 1–10 U/kg/h continuous infusion range based on the patient's weight, derived from the Engebretsen 2011 HIET protocol. Does not include dextrose selection, titration guidance, DigiFab, glucagon, or calcium recommendations.","failureModes":["Weight out of range (below 1 kg or above 500 kg for weight_kg; below 2 lb or above 1100 lb for weight_lb) returns an error","Neither weight_kg nor weight_lb provided returns a missing parameter error","Both weight parameters omitted results in a validation error","Non-numeric weight values cause a schema validation failure"],"whenToPreferThis":"Use this endpoint when you need a deterministic, citation-backed HIET insulin dose calculation based on patient weight for beta-blocker or calcium-channel-blocker cardiogenic shock. Prefer it over manual calculation to avoid arithmetic errors. It is not a substitute for clinical judgment, titration decisions, or adjunct therapy selection.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-15T06:56:32.975Z","isFirstParty":false}