{"uid":"cap_fQGCLm2KCkp1EDIw-Fa06","slug":"naloxone-drip-rate-calculator-goldfrank-1986-d21d5dd7","name":"Naloxone Drip Rate Calculator (Goldfrank 1986)","description":"Continuous intravenous naloxone infusion as two-thirds of the caller-assigned reversal bolus each hour (Goldfrank 1986). infusion_mg_h = (2/3) * reversal_bolus_mg maintains plasma naloxone at or above the 30-minute post-bolus level. magent does not choose the bolus or start naloxone. Not a prescription or medical device.","url":"https://api.magentlab.com/api/calc/naloxone_drip","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["reversal_bolus_mg"],"properties":{"reversal_bolus_mg":{"type":"number","description":"Caller-assigned naloxone reversal bolus in mg (0.04-10.0) that already resulted in reversal. magent does not choose the bolus."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_7yWJDtPiXgY7YR6_k3AN_","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Calculates continuous IV naloxone infusion rate as two-thirds of the caller-supplied reversal bolus dose per hour, per the Goldfrank 1986 protocol.","exampleAgentPrompt":"I just used a 0.8 mg naloxone bolus to reverse an opioid overdose — what should the continuous IV infusion rate be using the Goldfrank two-thirds rule?","exampleUseCases":[{"title":"ED opioid overdose drip setup","prompt":"A patient was reversed with a 0.4 mg naloxone bolus. What continuous IV naloxone infusion rate does the Goldfrank 1986 two-thirds formula give me?"},{"title":"High-dose reversal maintenance drip","prompt":"We used 2 mg of naloxone to reverse a fentanyl overdose. Calculate the hourly infusion rate for the maintenance drip using the two-thirds bolus rule."},{"title":"Pediatric reversal infusion rate check","prompt":"The reversal bolus used was 0.1 mg of naloxone. What continuous infusion rate does the Goldfrank protocol recommend to maintain plasma levels?"}],"resultDescription":"Returns the calculated continuous IV naloxone infusion rate in mg/hour, computed as (2/3) × reversal_bolus_mg, intended to maintain plasma naloxone at or above the 30-minute post-bolus level per the Goldfrank 1986 protocol.","failureModes":["Missing reversal_bolus_mg parameter returns a validation error","reversal_bolus_mg outside the 0.04–10.0 mg range may be rejected or flagged","Non-numeric input for reversal_bolus_mg causes a schema validation failure","Payment failure (x402 protocol) results in 402 response without computation"],"whenToPreferThis":"Use this endpoint when you need to programmatically apply the Goldfrank 1986 two-thirds rule for naloxone maintenance infusion and already have a clinician-assigned reversal bolus dose. Prefer this over manual calculation when integrating dosing support into a clinical decision-support pipeline or agent workflow that needs a reproducible, formula-based result.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T12:58:38.003Z","isFirstParty":false}