{"uid":"cap_eZVqN4ozaovaLS1QkMEX8","slug":"carg-toxicity-score-calculator-hurria-2011-dcf21817","name":"CARG Toxicity Score Calculator (Hurria 2011)","description":"Hurria 2011 Table 5 CARG toxicity: age ≥72 (+2), GI/GU (+2, not inverted), standard dose (+2), polychemotherapy (+2), Hb male <11 or female <10 g/dL (+3), caller-assigned Jelliffe CrCl <34 (+3; magent does not compute Jelliffe), hearing fair/worse (+2), ≥1 fall in 6 months (+3), limited walking 1 block (+2), help with meds (+1), decreased social activity (+1). Max 19. 0-5 low 30%, 6-9 intermediate 52%, 10-19 high 83%. Not the 2016 revision, not CRASH, not a chemo order.","url":"https://api.magentlab.com/api/calc/carg_tt","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["age","gi_or_gu","standard_dose","polychemotherapy","hemoglobin_g_dl","sex","jelliffe_crcl_ml_min","hearing_fair_or_worse","falls_last_6_months","limited_walking_one_block","needs_help_with_medications","decreased_social_activity"],"properties":{"age":{"type":"integer","description":"Age in years (18-120). Hurria 2011 Table 5: ≥72 scores 2. Derived in patients ≥65; magent still applies the ≥72 rule at any accepted age."},"sex":{"enum":["female","male"],"type":"string","description":"Sex used for the hemoglobin cutoff (female or male). Male <11 g/dL or female <10 g/dL scores 3."},"gi_or_gu":{"type":"boolean","description":"GI or GU cancer as assigned by the caller (Hurria 2011 Table 5). true scores 2. Lung, breast, GYN, and other cancers are 0. This is a risk factor present (+2), not inverted. magent does not assign cancer type from histology text."},"standard_dose":{"type":"boolean","description":"Standard chemotherapy dose as assigned by the caller (Hurria 2011 Table 5). true scores 2. Dose-reduced is 0. magent does not read a chemo order."},"hemoglobin_g_dl":{"type":"number","description":"Hemoglobin in g/dL (3-22). Male <11 or female <10 scores 3 (Hurria 2011 Table 5). 11.0 male and 10.0 female do not score."},"polychemotherapy":{"type":"boolean","description":"Polychemotherapy as assigned by the caller (Hurria 2011 Table 5). true scores 2."},"falls_last_6_months":{"type":"boolean","description":"≥1 fall in the last 6 months as assigned by the caller (Hurria 2011 Table 5). true scores 3. magent does not take a fall history."},"jelliffe_crcl_ml_min":{"type":"number","description":"Jelliffe ideal-weight creatinine clearance in mL/min as assigned by the caller (1-300). <34 scores 3 (Hurria 2011 Table 5). 34 does not score. magent does not compute Jelliffe."},"hearing_fair_or_worse":{"type":"boolean","description":"Hearing fair or worse as assigned by the caller (Hurria 2011 Table 5). true scores 2. magent does not examine hearing."},"decreased_social_activity":{"type":"boolean","description":"MOS decreased social activity limited at least sometimes as assigned by the caller (Hurria 2011 Table 5). true scores 1. magent does not administer MOS."},"limited_walking_one_block":{"type":"boolean","description":"MOS walking 1 block somewhat limited or limited a lot as assigned by the caller (Hurria 2011 Table 5). true scores 2. magent does not administer MOS."},"needs_help_with_medications":{"type":"boolean","description":"IADL taking medications some help or unable as assigned by the caller (Hurria 2011 Table 5). true scores 1. magent does not administer IADL."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_9B2kexhg9Qpuje7Kvs0Uj","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Computes the Cancer and Aging Research Group (CARG) chemotherapy toxicity score from 11 caller-supplied clinical flags and returns risk category (low/intermediate/high) with predicted grade 3–5 toxicity probability.","exampleAgentPrompt":"Calculate the CARG chemo toxicity score for a 76-year-old male with GI cancer, hemoglobin of 9.8 g/dL, Jelliffe CrCl of 28 mL/min, planned for standard-dose polychemotherapy, who had one fall in the last 6 months, rates his hearing as fair, needs help with his medications, and has had decreased social activity — he can still walk a full block.","exampleUseCases":[{"title":"Pre-chemo toxicity screening in clinic","prompt":"Before we start this 78-year-old female patient on standard-dose polychemotherapy for colorectal cancer, can you run her CARG score? Her hemoglobin is 9.2 g/dL, Jelliffe CrCl is 30 mL/min, she had two falls in the past 6 months, her hearing is poor, she needs help with medications, her social activity has decreased, and she can't walk a full block."},{"title":"Low-risk patient chemo clearance","prompt":"I want to confirm this 68-year-old male lung cancer patient is low risk before starting chemo. Hemoglobin 13.5 g/dL, Jelliffe CrCl 60 mL/min, no falls, normal hearing, independent with meds, socially active, can walk a block — it's standard-dose single-agent, not polychemotherapy."},{"title":"Documenting toxicity risk tier in oncology note","prompt":"For the oncology note, what CARG risk category is a 73-year-old female with GU cancer, hemoglobin 10.5 g/dL, CrCl 40 mL/min, no falls, hearing is good, dose-reduced chemotherapy (not standard), no polychemotherapy, needs help with meds, and decreased social activity but walks fine?"}],"resultDescription":"Returns the integer CARG total score (0–19), the risk tier (low 0–5, intermediate 6–9, or high 10–19), and the associated predicted grade 3–5 chemotherapy toxicity probability (approximately 30%, 52%, or 83% respectively), based on the Hurria 2011 Table 5 derivation cohort.","failureModes":["Missing required query parameter returns 400 error — all 12 fields are mandatory","Out-of-range hemoglobin (outside 3–22 g/dL) or age (outside 18–120) rejected","Invalid enum value for sex (must be 'male' or 'female') causes validation error","Caller must supply Jelliffe CrCl — magent does not compute it from creatinine/demographics","Boolean fields passed as strings instead of true/false may cause parse errors","This endpoint implements 2011 Hurria, not the 2016 revision — results will differ from tools using updated weights"],"whenToPreferThis":"Use this endpoint when you need the original Hurria 2011 CARG Table 5 integer score for geriatric oncology patients being considered for chemotherapy. Prefer it over general risk calculators when the clinical workflow requires an explicit toxicity risk tier (low/intermediate/high) with the published toxicity probabilities. Note that this is not the 2016 revised CARG, not CRASH, and does not generate chemotherapy orders or compute Jelliffe CrCl — those inputs must be supplied by the caller.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-15T01:21:16.723Z","isFirstParty":false}