{"uid":"cap_eP3u0eUi1uyWmWa3L3F6W","slug":"longevitypulse-longevity-drug-intelligence-9663e9da","name":"LongevityPulse Longevity Drug Intelligence","description":"Longevity drug / anti-aging pharmaceutical intelligence (rapamycin, metformin, acarbose, senolytics, SGLT2 inhibitors, GLP-1 agonists) for longevity and health agents. Evidence-graded analysis of drugs studied for healthspan, with human-vs-animal evidence and global availability. Health intelligence, not medical advice.","url":"https://longevitypulse.vercel.app/api/longevity/longevity-drug","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"queryParams":{"type":"object","properties":{"drug":{"type":"string","description":"Drug name — e.g. \"rapamycin\" | \"metformin\" | \"acarbose\" | \"dasatinib\" | \"fisetin\" | \"senolytics\" | \"SGLT2 inhibitor\" | \"empagliflozin\" | \"GLP-1\" | \"semaglutide\""},"lang":{"type":"string","description":"en | es | fr | de | ja | zh | ko | pt | ar | hi (default: en)"}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"errors":{"type":"object","description":"Documented error responses, keyed by HTTP status code","additionalProperties":{"type":"object","required":["description"],"properties":{"example":{"type":"object"},"description":{"type":"string"}}}},"example":{"type":"object"}}}}},"responseSchema":{"type":"json","example":{"compound":"Rapamycin (Sirolimus)","drug_class":"mTOR inhibitor (macrolide)","fda_approved_for":"Organ transplant rejection prevention; certain cancers","longevity_use_case":"mTOR inhibition mimics caloric restriction — the most robust longevity intervention across species. Shown to extend lifespan in every animal model tested.","global_availability":{"prescription_status":"Prescription-only globally; Schedule F in US; available but off-label use varies by country"},"evidence_for_longevity":{"animal_evidence":{"lifespan_extension":"9-23% median lifespan extension in mice (ITP trials 2009, 2013, 2016) — even when started late in life"}}}},"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.2","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.2/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.2","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.2","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_JYMhmOuL_JhTbeySW1cZQ","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.2","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Returns evidence-graded longevity drug analysis covering human vs animal data, mechanisms, and global availability for pharmaceuticals like rapamycin, metformin, senolytics, and GLP-1 agonists","exampleAgentPrompt":"What does the evidence show for rapamycin as a longevity drug — is the human evidence strong, how does it compare to the animal data, and can I actually get it in Europe?","exampleUseCases":null,"resultDescription":"Returns an evidence-graded profile of the requested longevity drug including mechanism of action, strength of human vs animal evidence, healthspan and lifespan effects observed in studies, known risks or considerations, and information on global pharmaceutical availability.","failureModes":["Unknown or unsupported drug name returns no results or an error","Drug with only preclinical data may have sparse human evidence section","Payment failure (402) if USDC payment not attached","Network timeout if the vercel deployment is cold-starting"],"whenToPreferThis":"Use this endpoint when you need structured, evidence-graded intelligence specifically about pharmaceuticals studied for longevity and healthspan extension — particularly when the user wants to know whether human trial data exists vs only animal studies, or wants to understand global availability. Prefer this over general medical databases when the focus is geroscience and anti-aging pharmacology.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-15T06:35:08.872Z","isFirstParty":false}