{"uid":"cap_eA4bd4-AuPwoDxvZHEY8O","slug":"glucocorticoid-steroid-dose-converter-meikle-1977-4d7e74b3","name":"Glucocorticoid Steroid Dose Converter (Meikle 1977)","description":"Convert a glucocorticoid milligram dose among hydrocortisone, prednisone, and dexamethasone using Meikle 1977 equivalent doses (20 : 5 : 0.75). Not a taper, stress-dose protocol, or regimen recommendation; mineralocorticoid activity is not converted. Deterministic published table with citation.","url":"https://api.magentlab.com/api/calc/steroid_conversion","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["from","to","dose_mg"],"properties":{"to":{"enum":["hydrocortisone","prednisone","dexamethasone"],"type":"string","description":"Target glucocorticoid. hydrocortisone, prednisone, or dexamethasone (Meikle 1977)."},"from":{"enum":["hydrocortisone","prednisone","dexamethasone"],"type":"string","description":"Source glucocorticoid. hydrocortisone, prednisone, or dexamethasone (Meikle 1977)."},"dose_mg":{"type":"number","description":"Dose of the source glucocorticoid in milligrams (0.1-5000)."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":{"type":"json","example":{"path":"/api/calc/steroid_conversion","count":2,"items":[{"to":"prednisone","from":"hydrocortisone","dose_mg":20,"formula":"steroid_conversion","citation":{"id":"meikle-1977","doi":"10.1016/0002-9343(77)90233-9","title":"Potency and duration of action of glucocorticoids. Effects of hydrocortisone, prednisone and dexamethasone on human pituitary-adrenal function","source":"Am J Med. 1977;63(2):200-207","authors":"Meikle AW, Tyler FH"},"disclaimer":"Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.","to_equivalent_mg":5,"equivalent_dose_mg":5,"formula_expression":"equivalent_dose_mg = dose_mg * (to_equivalent_mg / from_equivalent_mg); hydrocortisone 20 mg = prednisone 5 mg = dexamethasone 0.75 mg (Meikle 1977)","from_equivalent_mg":20},{"to":"prednisone","from":"hydrocortisone","dose_mg":20,"formula":"steroid_conversion","citation":{"id":"meikle-1977","doi":"10.1016/0002-9343(77)90233-9","title":"Potency and duration of action of glucocorticoids. Effects of hydrocortisone, prednisone and dexamethasone on human pituitary-adrenal function","source":"Am J Med. 1977;63(2):200-207","authors":"Meikle AW, Tyler FH"},"disclaimer":"Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.","to_equivalent_mg":5,"equivalent_dose_mg":5,"formula_expression":"equivalent_dose_mg = dose_mg * (to_equivalent_mg / from_equivalent_mg); hydrocortisone 20 mg = prednisone 5 mg = dexamethasone 0.75 mg (Meikle 1977)","from_equivalent_mg":20}]}},"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_6cOhhsPL37z9XnHTplzxo","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Converts a glucocorticoid milligram dose between hydrocortisone, prednisone, and dexamethasone using the Meikle 1977 equivalency ratios (20:5:0.75).","exampleAgentPrompt":"My patient is on 40mg of prednisone daily — what's the equivalent dose in hydrocortisone using standard glucocorticoid equivalency tables?","exampleUseCases":[{"title":"Prednisone to dexamethasone crossover","prompt":"I need to switch a patient from 60mg prednisone to dexamethasone — what's the equivalent dexamethasone dose based on the Meikle equivalency ratios?"},{"title":"Hydrocortisone stress dosing reference check","prompt":"We're documenting a patient on 100mg hydrocortisone — what would the equivalent prednisone dose be so I can note it for the care team?"},{"title":"Dexamethasone back-calculation to prednisone","prompt":"A patient received 4mg dexamethasone — what's that in prednisone milligrams so I can document the glucocorticoid exposure in prednisone-equivalent terms?"}],"resultDescription":"Returns the equivalent dose in the target glucocorticoid in milligrams, calculated using the Meikle 1977 published equivalency ratios (hydrocortisone 20 : prednisone 5 : dexamethasone 0.75), along with the source and target drug names and the authoritative citation.","failureModes":["Invalid 'from' or 'to' steroid name not in the enum (hydrocortisone, prednisone, dexamethasone) returns an error","dose_mg outside allowed range (0.1–5000 mg) returns a validation error","Same drug specified for both 'from' and 'to' may return a trivial 1:1 result or an error","Missing required query parameters returns a 400-level error","Network or payment failure returns no result"],"whenToPreferThis":"Choose this endpoint when you need a deterministic, citation-backed glucocorticoid dose equivalency calculation among hydrocortisone, prednisone, and dexamethasone. It is ideal for clinical documentation, pharmacy reconciliation, or agent workflows requiring a published reference (Meikle 1977) rather than an LLM estimate. Do not use it for taper schedules, stress-dose protocols, mineralocorticoid equivalency, or steroids outside the three supported drugs.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-15T01:03:47.284Z","isFirstParty":false}