{"uid":"cap_byAgpj3-7h2JXgtTDycqK","slug":"2s-medical-genetics-lookup-17f0a93b","name":"2s Medical Genetics Lookup","description":"MedlinePlus Genetics (US National Library of Medicine) reference on a genetic condition or gene. Give a term (e.g. \"cystic fibrosis\", \"BRCA1\", \"sickle cell\") and get back the authoritative NLM record: the condition/gene name, a plain-language summary, the full set of sections (description, causes, frequency, inheritance, treatment), the inheritance pattern(s), related genes (with links), synonyms, and cross-references to other databases (OMIM, GTR, ICD-10-CM, …). Free, public-domain (NLM). Authoritative genetics reference an LLM cannot recite reliably — for clinical, patient-education, and research agents. Educational reference, not medical advice.","url":"https://2s.io/api/medical/genetics","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method","queryParams"],"properties":{"type":{"const":"http"},"method":{"const":"GET"},"queryParams":{"required":["term"],"properties":{"term":{"type":"string","description":"Condition or gene name (e.g. \"cystic fibrosis\", \"BRCA1\")."}}}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.00108","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"settled","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.00108/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.0027","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.0027","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_NSti4xnka8B1Haohi9WJ-","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.0027","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Looks up genetic conditions or genes by name, returning structured summaries, related genes, synonyms, inheritance patterns, and cross-references from MedlinePlus Genetics.","exampleAgentPrompt":"Look up the genetics of cystic fibrosis — I need a summary, the inheritance pattern, related genes like CFTR, synonyms, and any ICD-10 cross-references.","exampleUseCases":null,"resultDescription":"Returns an array of matching genetic conditions or genes, each with a plain-language summary, synonyms, related gene symbols with URLs, cross-references to databases like ICD-10-CM and GTR, inheritance patterns (e.g. autosomal recessive), and structured text sections. Also includes total result count and source attribution from MedlinePlus Genetics.","failureModes":["No matching condition or gene found for the search term — returns empty items array","Ambiguous term matches many results — agent may need to refine the query","Payment failure via x402 — 402 response if USDC not provided","Network timeout or upstream MedlinePlus unavailability — 5xx error"],"whenToPreferThis":"Use this endpoint when an agent needs authoritative, ground-truth genetic data about a condition or gene — including inheritance patterns, synonyms, related genes, and cross-database references — sourced from the U.S. National Library of Medicine. Prefer over general web search when structured, machine-readable genetics data is required.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":2,"lastUsedAt":"2026-07-17T20:07:53.829Z","lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T06:44:22.379Z","isFirstParty":false}