{"uid":"cap_aOk4ngxPLPYeeBjshHaa0","slug":"health-memoryapi-org-e4e30b6d","name":"Human Protein Atlas — Gene/Protein Expression by Tissue and Brain Region","description":"Health and biomedical data API powered by x402 micropayments. Access NIH grants, WHO health statistics, ClinVar genetic variants, and Human Protein Atlas expression data.","url":"https://health.memoryapi.org/x402/health/protein","method":"GET","headers":{},"bodySchema":{"properties":{"input":{"properties":{"method":{"type":"string","enum":["GET"]}},"required":["method"]}}},"responseSchema":{"example":{"gene":"BRCA1","success":true,"proteins":[{"gene":"BRCA1","ensembl":"ENSG00000012048","uniprot":"P38398","top_tissues":[{"value":12.4,"tissue":"breast"}]}],"results_count":1}},"example":{"request":{"gene":"APOE","type":"expression"},"response":{"gene":"APOE","source":"Human Protein Atlas","success":true,"proteins":[{"gene":"APOE","ensembl":"ENSG00000130203","uniprot":["P02649"],"top_tissues":[],"brain_regions":[]},{"gene":"LRP1","ensembl":"ENSG00000123384","uniprot":["Q07954"],"top_tissues":[],"brain_regions":[]},{"gene":"LRP8","ensembl":"ENSG00000157193","uniprot":["Q14114"],"top_tissues":[],"brain_regions":[]},{"gene":"MALRD1","ensembl":"ENSG00000204740","uniprot":["Q5VYJ5"],"top_tissues":[],"brain_regions":[]},{"gene":"COX17","ensembl":"ENSG00000138495","uniprot":["Q14061"],"top_tissues":[],"brain_regions":[]},{"gene":"SELENOP","ensembl":"ENSG00000250722","uniprot":["P49908"],"top_tissues":[],"brain_regions":[]}],"results_count":6}},"exampleRequest":{"gene":"APOE","type":"expression"},"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"settled","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_q52xCab-XtmOP8AxmBd0m","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Returns gene and protein expression data across human tissues and brain regions from the Human Protein Atlas database.","exampleAgentPrompt":"Look up the Human Protein Atlas expression data for the gene APOE and tell me which tissues and brain regions show the highest protein expression levels.","exampleUseCases":null,"resultDescription":"Returns protein and gene expression data for the queried gene or protein across human tissues and brain regions, including expression scores, tissue names, and regional specificity data sourced from the Human Protein Atlas.","failureModes":["Unknown gene or protein name returns empty or error response","Misspelled gene symbol returns no results","Rate limiting or payment failure returns 402 status","Unsupported tissue or brain region filter returns empty results","Gene exists but has no expression data in the atlas"],"whenToPreferThis":"Use this endpoint when you need structured, curated protein or gene expression data across human tissues and brain regions, particularly for biomedical research, drug target analysis, or understanding where a specific gene is active in the body. Prefer this over general genomics APIs when you specifically need tissue-level or brain-region-level protein expression from the Human Protein Atlas.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-15T06:34:08.945Z","isFirstParty":false}