{"uid":"cap_aH5ECCmEpoabO26t7NNOh","slug":"magent-hct-ci-calculator-sorror-2005-cf585363","name":"magent HCT-CI Calculator (Sorror 2005)","description":"Sorror 2005 HCT-specific comorbidity index. Seventeen caller-assigned comorbidities with published weights 1, 2, or 3 (max 26). Pulmonary moderate vs severe and hepatic mild vs moderate/severe are mutually exclusive. Risk groups: 0 low, 1–2 intermediate, ≥3 high. Caller supplies the published category; magent does not interpret PFTs or echo and does not list for transplant. Not Charlson. Not a diagnosis. Not a medical device.","url":"https://api.magentlab.com/api/calc/hct_ci","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["arrhythmia","cardiac","inflammatory_bowel_disease","diabetes","cerebrovascular_disease","psychiatric_disturbance","mild_hepatic","obesity","infection","rheumatologic","peptic_ulcer","moderate_severe_renal","moderate_pulmonary","prior_solid_tumor","heart_valve_disease","severe_pulmonary","moderate_severe_hepatic"],"properties":{"cardiac":{"type":"boolean","description":"Cardiac comorbidity as assigned by the caller (Sorror 2005: coronary artery disease, congestive heart failure, myocardial infarction, or ejection fraction ≤50%). true scores 1. magent does not interpret echo or diagnose cardiac disease."},"obesity":{"type":"boolean","description":"Obesity as assigned by the caller (Sorror 2005: body mass index >35 kg/m²). true scores 1. magent does not compute BMI."},"diabetes":{"type":"boolean","description":"Diabetes requiring insulin or oral hypoglycemics, not diet alone, as assigned by the caller (Sorror 2005). true scores 1. magent does not diagnose diabetes."},"infection":{"type":"boolean","description":"Infection requiring continuation of antimicrobial treatment after day 0 as assigned by the caller (Sorror 2005). true scores 1. magent does not diagnose infection."},"arrhythmia":{"type":"boolean","description":"Arrhythmia as assigned by the caller (Sorror 2005: atrial fibrillation or flutter, sick sinus syndrome, or ventricular arrhythmias). true scores 1. magent does not diagnose arrhythmia."},"mild_hepatic":{"type":"boolean","description":"Mild hepatic comorbidity as assigned by the caller (Sorror 2005: chronic hepatitis, bilirubin >ULN to 1.5×ULN, or AST/ALT >ULN to 2.5×ULN). true scores 1. Mutually exclusive with moderate_severe_hepatic. magent does not grade liver tests."},"peptic_ulcer":{"type":"boolean","description":"Peptic ulcer requiring treatment as assigned by the caller (Sorror 2005). true scores 2. magent does not diagnose ulcer disease."},"rheumatologic":{"type":"boolean","description":"Rheumatologic comorbidity as assigned by the caller (Sorror 2005: SLE, RA, polymyositis, mixed CTD, or polymyalgia rheumatica). true scores 2. magent does not diagnose rheumatologic disease."},"severe_pulmonary":{"type":"boolean","description":"Severe pulmonary comorbidity as assigned by the caller (Sorror 2005: DLco and/or FEV1 ≤65% or dyspnea at rest or requiring oxygen). true scores 3. Mutually exclusive with moderate_pulmonary. magent does not interpret PFTs."},"prior_solid_tumor":{"type":"boolean","description":"Prior solid tumor treated at any time, excluding nonmelanoma skin cancer, as assigned by the caller (Sorror 2005). true scores 3. magent does not diagnose cancer."},"moderate_pulmonary":{"type":"boolean","description":"Moderate pulmonary comorbidity as assigned by the caller (Sorror 2005: DLco and/or FEV1 66%–80% or dyspnea on slight activity). true scores 2. Mutually exclusive with severe_pulmonary. magent does not interpret PFTs."},"heart_valve_disease":{"type":"boolean","description":"Heart valve disease except mitral valve prolapse as assigned by the caller (Sorror 2005). true scores 3. magent does not interpret echo."},"moderate_severe_renal":{"type":"boolean","description":"Moderate/severe renal comorbidity as assigned by the caller (Sorror 2005: serum creatinine >2 mg/dL, dialysis, or prior renal transplantation). true scores 2. magent does not grade kidney disease from creatinine."},"cerebrovascular_disease":{"type":"boolean","description":"Cerebrovascular disease as assigned by the caller (Sorror 2005: TIA or cerebrovascular accident). true scores 1. magent does not diagnose stroke or TIA."},"moderate_severe_hepatic":{"type":"boolean","description":"Moderate/severe hepatic comorbidity as assigned by the caller (Sorror 2005: cirrhosis, bilirubin >1.5×ULN, or AST/ALT >2.5×ULN). true scores 3. Mutually exclusive with mild_hepatic. magent does not grade liver tests."},"psychiatric_disturbance":{"type":"boolean","description":"Psychiatric disturbance as assigned by the caller (Sorror 2005: depression or anxiety requiring psychiatric consult or treatment). true scores 1. magent does not diagnose psychiatric disease."},"inflammatory_bowel_disease":{"type":"boolean","description":"Inflammatory bowel disease as assigned by the caller (Sorror 2005: Crohn disease or ulcerative colitis). true scores 1. magent does not diagnose IBD."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm__I2Cb79uUO6NpNmBNBSdx","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Computes the hematopoietic cell transplantation-specific comorbidity index (HCT-CI) from 17 caller-assigned boolean comorbidities and returns a weighted total score with risk group classification.","exampleAgentPrompt":"Calculate the HCT-CI score for a patient with cardiac disease, moderate pulmonary disease, diabetes, and mild hepatic disease — no arrhythmia, no infection, no obesity, no inflammatory bowel disease, no cerebrovascular disease, no psychiatric disturbance, no rheumatologic disease, no peptic ulcer, no moderate-severe renal disease, no prior solid tumor, no heart valve disease, no severe pulmonary, and no moderate-severe hepatic disease — and tell me the total score and risk group.","exampleUseCases":[{"title":"Pre-transplant risk stratification","prompt":"I have a stem cell transplant candidate with arrhythmia, obesity, and moderate-severe renal disease — all other HCT-CI comorbidities are absent. What is their Sorror HCT-CI score and what risk group do they fall into?"},{"title":"Comorbidity index for research cohort","prompt":"For a patient in our allogeneic HCT study cohort who has cardiac disease, diabetes, mild hepatic disease, and a prior solid tumor but none of the other 13 Sorror comorbidities, what is the HCT-CI total and risk classification?"},{"title":"Comparing two transplant candidates","prompt":"Calculate the HCT-CI for two patients: first, someone with severe pulmonary disease and moderate-severe hepatic disease only; second, someone with only arrhythmia and peptic ulcer. Give me both scores and risk groups so I can compare transplant risk."}],"resultDescription":"Returns the integer HCT-CI total score (0–26) and a risk group label — low (0), intermediate (1–2), or high (≥3) — derived from the 17 weighted boolean comorbidity flags supplied by the caller. Individual per-comorbidity weights (1, 2, or 3 per Sorror 2005 published table) are reflected in the aggregate. No diagnosis, no lab interpretation, and no listing recommendation is generated.","failureModes":["Missing any of the 17 required boolean query parameters returns a validation error","Supplying both mild_hepatic and moderate_severe_hepatic as true may return a mutual-exclusivity error (these are defined as mutually exclusive in Sorror 2005)","Supplying both moderate_pulmonary and severe_pulmonary as true may similarly trigger a mutual-exclusivity error","Non-boolean or malformed parameter values return a schema validation error","Payment failure (x402) results in a 402 response with no score returned"],"whenToPreferThis":"Use this endpoint when you need a programmatic, reproducible HCT-CI calculation per Sorror 2005 and the caller has already clinically assigned each of the 17 comorbidity categories. Prefer it over manual lookup tables to avoid arithmetic errors and ensure consistent risk-group thresholds. Do not use it as a substitute for clinical judgment, PFT interpretation, echocardiography reading, or diagnosis — the caller must supply pre-classified boolean flags.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-16T01:00:15.165Z","isFirstParty":false}