{"uid":"cap_ZeT6HgrNXjGJB9M1ANIpo","slug":"gene-summary-lookup-by-ncbi-gene-id-or-symbol-304f6dea","name":"Gene Summary Lookup by NCBI Gene ID or Symbol","description":"Describe a gene from its NCBI Gene ID or official symbol: name, aliases, organism, position on the genome and a summary of its function.","url":"https://win.oneshotagent.com/v1/tools/lookup/gene-summary?utm_source=zero.xyz","method":"POST","headers":{},"bodySchema":{"type":"object","properties":{"symbol":{"type":"string","description":"An official gene symbol, for example TP53, matched without regard to case in the organism `taxon_id` names. 1 to 30 characters. No spaces, quotes or square brackets."},"gene_id":{"type":"string","description":"An NCBI Gene ID, digits only, for example 7157. Digits only, 1 to 12."},"taxon_id":{"type":"integer","description":"The organism as an NCBI Taxonomy ID, used with `symbol`; 9606 (human) unless set, 10090 is mouse. From 1 to 999999999. Defaults to `9606`."}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_ovtNnztZbtq7FHh6OCb-Q","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Returns structured gene information (name, aliases, organism, genomic position, and functional summary) given an NCBI Gene ID or official gene symbol.","exampleAgentPrompt":"Can you look up the TP53 gene (human, taxon ID 9606) and give me its official name, aliases, chromosomal position, and a summary of what it does?","exampleUseCases":[{"title":"Bioinformatics pipeline gene annotation","prompt":"I have a list of NCBI Gene IDs from my RNA-seq analysis — starting with gene ID 7157. Can you pull the official name, aliases, genomic position, and functional summary for it?"},{"title":"Research background on disease gene","prompt":"I'm writing about hereditary breast cancer — can you look up BRCA1 in humans and give me its official name, any aliases, where it sits on the genome, and a plain-English summary of what it does?"},{"title":"Cross-species gene comparison","prompt":"Can you look up the mouse version of Trp53 (taxon ID 10090) — I need its official symbol, aliases, chromosomal location, and functional description so I can compare it to the human TP53 gene?"}],"resultDescription":"Returns structured gene metadata including the official gene name, known aliases, the organism it belongs to, its chromosomal/genomic position, and a text summary of its biological function — sourced from the NCBI Gene database.","failureModes":["Gene symbol not found for given taxon ID — returns not-found or empty result","Invalid or non-existent NCBI Gene ID — returns error or empty response","Ambiguous gene symbol matching multiple genes — may return unexpected record","Invalid taxon ID format — returns validation error","Gene ID contains non-digit characters — schema validation failure"],"whenToPreferThis":"Use this endpoint when an agent needs authoritative gene metadata (name, position, function) from NCBI for a known gene symbol or Gene ID. Prefer over manual NCBI web searches when structured, machine-readable gene data is required. Particularly useful when integrating gene annotations into bioinformatics pipelines, research summaries, or when cross-referencing gene identities across organisms.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-10-20T12:38:38.183Z","isFirstParty":false,"canonicalSlug":"gene-summary-lookup-by-ncbi-gene-id-or-symbol-304f6dea"}