{"uid":"cap_VqsRSEtrMZq7fSv7XyLaS","slug":"sedan-score-calculator-for-sich-after-stroke-thrombolysis-bfff4ae9","name":"SEDAN Score Calculator for sICH After Stroke Thrombolysis","description":"SEDAN (Strbian 2012 Ann Neurol) for sICH after stroke thrombolysis. Glucose 8.1-12.0 mmol/L (1) or >12.0 (2); early infarct signs (1); hyperdense cerebral artery (1); age >75 (1); admission NIHSS ≥10 (1); max 6. Derivation absolute sICH 1.4%, 2.9%, 8.5%, 12.2%, 21.7%, 33.3% for scores 0-5; no published percent for 6. Not a tPA withhold decision. magent does not assign NIHSS or read CT.","url":"https://api.magentlab.com/api/calc/sedan","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["age","nihss","early_infarct_signs","hyperdense_artery"],"properties":{"age":{"type":"integer","description":"Age in years (18-120). >75 scores 1; 75 does not (Strbian 2012). magent does not date the patient."},"nihss":{"type":"integer","description":"Caller-assigned NIH Stroke Scale total (integer 0-42). ≥10 scores 1; 9 does not. magent does not compute NIHSS or examine the patient."},"glucose_mg_dl":{"type":"number","description":"Baseline glucose in mg/dL (50-1000). Converted as mmol/L = mg/dL / 18. Provide this or glucose_mmol_l, not both."},"glucose_mmol_l":{"type":"number","description":"Baseline glucose in mmol/L (2.8-55.5). Provide this or glucose_mg_dl, not both. 8.1-12.0 inclusive scores 1; >12.0 scores 2; else 0 (Strbian 2012)."},"hyperdense_artery":{"type":"boolean","description":"(Hyper)dense cerebral artery sign on admission CT as assigned by the caller (Strbian 2012). true scores 1; false scores 0. magent does not read the CT."},"early_infarct_signs":{"type":"boolean","description":"Early infarct signs on admission CT as assigned by the caller (Strbian 2012). true scores 1; false scores 0. magent does not read the CT."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_pxhWotoPopM3Oi5QDoMTa","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Computes the SEDAN score (Strbian 2012) to estimate risk of symptomatic intracranial hemorrhage (sICH) after IV tPA thrombolysis for ischemic stroke","exampleAgentPrompt":"Calculate the SEDAN score for a 78-year-old stroke patient with an admission NIHSS of 14, glucose of 10.2 mmol/L, early infarct signs present on CT, and no hyperdense cerebral artery sign — I need the sICH risk estimate before we proceed with tPA.","exampleUseCases":[{"title":"Pre-tPA sICH risk stratification in ED","prompt":"My stroke patient is 82 years old, NIHSS is 16, admission glucose is 13.5 mmol/L, early infarct signs are present on CT, and the hyperdense MCA sign is also present — what's their SEDAN score and expected sICH risk if we give tPA?"},{"title":"Low-risk thrombolysis candidate assessment","prompt":"Can you calculate the SEDAN score for a 65-year-old with NIHSS of 7, glucose of 6.4 mmol/L, no early infarct signs, and no hyperdense artery on CT? I want to document the sICH risk estimate in the chart."},{"title":"Borderline glucose elevation impact on SEDAN","prompt":"Our patient is 76 years old, NIHSS 11, glucose is 9.0 mmol/L, no hyperdense artery, early infarct signs present — compute the SEDAN score so I can see how the borderline glucose affects the overall hemorrhage risk."}],"resultDescription":"Returns the total SEDAN score (integer 0–6) and the corresponding published absolute sICH risk percentage from the Strbian 2012 derivation cohort (1.4% for 0, 2.9% for 1, 8.5% for 2, 12.2% for 3, 21.7% for 4, 33.3% for 5; no published percent for score 6). The score is advisory only and does not constitute a tPA withhold decision.","failureModes":["Missing required parameters (age, nihss, early_infarct_signs, hyperdense_artery) returns a validation error","Providing both glucose_mg_dl and glucose_mmol_l simultaneously is rejected","Age or NIHSS outside expected integer range may return an error or unexpected result","Glucose outside the accepted range (2.8–55.5 mmol/L or 50–1000 mg/dL) may be rejected","Score 6 returns no published sICH percentage as none exists in the Strbian 2012 paper"],"whenToPreferThis":"Use this endpoint when you need a fast, reproducible SEDAN score calculation from structured clinical inputs (age, NIHSS, glucose, CT findings) and want to avoid manual arithmetic errors. Prefer this over generic medical calculators when you specifically need the Strbian 2012 sICH-after-tPA risk score with the published absolute risk percentages. Not intended to replace clinical judgment or serve as a standalone tPA withhold decision tool.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-16T00:47:12.944Z","isFirstParty":false}