{"uid":"cap_TsY7J2oKdtbJc00O9L1RU","slug":"oracles-clinical-trials-changes-feed-4903e9b4","name":"Oracles Clinical Trials Changes Feed","description":"Newly registered clinical studies since a timestamp, scored by phase and sponsor class (Phase 3/4 industry trials score highest), with condition, sponsor, enrollment, and NCT link — competitive intelligence for pharma/biotech agents.","url":"https://oracles-production.up.railway.app/v1/clinical-trials/changes","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET"],"type":"string"},"queryParams":{"type":"object","properties":{"limit":{"type":"integer","maximum":500,"minimum":1},"since":{"type":"string","format":"date-time","description":"Only changes detected after this ISO-8601 instant"},"min_significance":{"type":"integer","maximum":10,"minimum":1,"description":"Keep only changes scored at least this"}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object","properties":{"count":{"type":"integer"},"source":{"type":"string"},"changes":{"type":"array","items":{"type":"object","properties":{"type":{"type":"string"},"title":{"type":"string"},"detail":{"type":"object"},"summary":{"type":"string"},"entityId":{"type":"string"},"sourceUrl":{"type":["string","null"],"description":"Primary-source link for verification"},"detectedAt":{"type":"string","format":"date-time"},"significance":{"type":"integer","maximum":10,"minimum":1},"effectiveDate":{"type":["string","null"]}}}}}}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.05","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.05/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.05","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.05","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_x0GdYJe793gppuFzCsQii","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.05","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Returns newly registered clinical studies since a given timestamp, each scored by phase and sponsor class for pharma/biotech competitive intelligence.","exampleAgentPrompt":"Show me all newly registered clinical trials since 2025-01-01T00:00:00Z with a significance score of at least 7 — I want Phase 3 and Phase 4 industry-sponsored studies, up to 100 results, so I can do competitive intelligence for our oncology pipeline.","exampleUseCases":null,"resultDescription":"A JSON object with a count of changes and an array of clinical trial change records, each including the study title, NCT ID, condition, sponsor, enrollment, phase, significance score (1-10), detected timestamp, effective date, and a direct ClinicalTrials.gov source URL for verification.","failureModes":["Missing or malformed 'since' date-time returns a 400 error","'limit' exceeding 500 or below 1 returns a validation error","'min_significance' outside 1-10 range returns a validation error","No trials found in the window returns an empty changes array with count 0","Payment not provided or invalid x402 payment returns a 402 Payment Required","Upstream ClinicalTrials.gov data unavailable may return 503 or stale data"],"whenToPreferThis":"Use this endpoint when you need structured, pre-scored clinical trial registration data with competitive intelligence weighting (Phase 3/4 industry trials scored highest), rather than querying ClinicalTrials.gov directly. Prefer this over raw registry APIs when you want significance-filtered, change-detected results since a specific timestamp without writing your own scoring logic. Best for pharma/biotech agents doing automated competitive monitoring or pipeline analysis.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-15T13:07:01.369Z","isFirstParty":false}