{"uid":"cap_RI1278GLnFMgJItbvL7gm","slug":"saylor-innovations-human-phenotype-ontology-search-3e39247a","name":"Saylor Innovations Human Phenotype Ontology Search","description":"Search the Human Phenotype Ontology for clinical signs and symptoms - HP id, name, definition and synonyms with a link to each term page","url":"https://saylorinnovations.com/api/bio/phenotype-search?utm_source=zero.xyz","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET"],"type":"string"},"queryParams":{"type":"object","required":["q"],"properties":{"q":{"type":"string","description":"Symptom or clinical sign"},"limit":{"type":"string","description":"optional 1-25, default 10"}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string","const":"json"},"example":{"type":"object","required":["query","phenotypes"],"properties":{"note":{"type":"string","description":"Caveat or context for reading the result"},"count":{"type":"number","description":"Number of items returned"},"query":{"type":"string","description":"The query as the server interpreted it"},"total":{"type":"number","description":"Total number of matching items"},"source":{"type":"string","description":"Data source the values come from"},"phenotypes":{"type":"array","description":"Matching Human Phenotype Ontology terms with id, name, definition and synonyms"}}}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.01","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.01/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.01","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.01","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_tXOhj_Ya72uJdLEeA9VEd","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.01","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Search the Human Phenotype Ontology (HPO) for clinical signs and symptoms, returning HP IDs, names, definitions, synonyms, and term page links","exampleAgentPrompt":"Search the Human Phenotype Ontology for 'muscle weakness' and return up to 15 matching terms with their HP IDs, definitions, and synonyms.","exampleUseCases":[{"title":"Rare disease phenotype coding","prompt":"I need to find the official HPO terms and HP IDs for 'abnormal eye movement' — can you search the Human Phenotype Ontology and give me the top 5 results with definitions?"},{"title":"Clinical NLP entity linking","prompt":"I have a clinical note that mentions 'hearing loss' — search the Human Phenotype Ontology for that symptom so I can map it to the correct HP code and synonyms."},{"title":"Genomics research symptom lookup","prompt":"Can you look up 'intellectual disability' in the Human Phenotype Ontology and return the matching terms with their IDs and definitions? I need about 10 results."}],"resultDescription":"A JSON object containing the interpreted query string, total number of matching HPO terms, count of returned items, the data source attribution, and an array of phenotype objects each with an HP term ID, name, full definition, list of synonyms, and a link to the HPO term page.","failureModes":["Missing required query parameter 'q' returns a 400 error","Query returns zero results if the symptom string does not match any HPO term","Limit parameter outside 1–25 range may return default of 10 results","Ambiguous or misspelled symptom terms may return irrelevant HPO entries","Payment failure or missing x402 header results in 402 Payment Required"],"whenToPreferThis":"Use this endpoint when you need structured, standards-based phenotype terminology from the Human Phenotype Ontology — particularly for rare disease research, clinical NLP entity linking, genomics workflows, or any use case requiring official HP IDs, term definitions, and synonyms. Prefer this over free-text medical databases when ontology compliance and HP code accuracy matter.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-10-18T12:56:43.203Z","isFirstParty":false,"canonicalSlug":"saylor-innovations-human-phenotype-ontology-search-3e39247a"}