{"uid":"cap_QHNbyo6_F197RZ3WZmSI9","slug":"pubmed-biomedical-literature-search-e64eb7b7","name":"PubMed Biomedical Literature Search","description":"Searches PubMed for biomedical literature by free-text query, with optional date range and sort (relevance / pub_date / first_author). Returns total hit count plus PMID, title, authors, journal, publication date, abstract, MeSH terms, and DOI per paper. Federal public-domain data via NCBI. Use it as a medical journal lookup, NIH paper search, clinical-research finder, MeSH-term query, or NCBI E-utilities wrapper.","url":"https://x402.agentutility.ai/pubmed-search?utm_source=zero.xyz","method":"POST","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method","bodyType","body"],"properties":{"body":{"required":["query"],"properties":{"sort":{"enum":["relevance","pub_date","first_author"],"type":"string","description":"Result ordering. Default 'relevance'."},"limit":{"type":"number","description":"Max papers to return. 1-50. Default 10."},"query":{"type":"string","description":"PubMed query string. Supports field tags ('cancer[Title]', 'Smith J[Author]'), boolean operators, and MeSH terms."},"date_to":{"type":"string","description":"Upper bound on publication date (YYYY/MM/DD or YYYY-MM-DD)."},"date_from":{"type":"string","description":"Lower bound on publication date (YYYY/MM/DD or YYYY-MM-DD)."},"include_abstract":{"type":"boolean","description":"If true (default), include the abstract text per paper. Set false for a smaller, faster response."}}},"type":{"type":"string","const":"http"},"method":{"enum":["POST"],"type":"string"},"bodyType":{"enum":["json","form-data","text"],"type":"string"}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object","properties":{"sort":{"type":"string"},"query":{"type":"string"},"total":{"type":"integer"},"papers":{"type":"array","items":{"type":"object","properties":{"pmid":{"type":"string"},"title":{"type":"string"},"authors":{"type":"array","items":{"type":"string"}}}}},"source":{"type":"string"},"date_to":{"type":"null"},"returned":{"type":"integer"},"date_from":{"type":"null"}}}}}}},"responseSchema":{"type":"json","example":{"sort":"relevance","query":"CRISPR sickle cell","total":451,"papers":[{"pmid":"33283989","title":"CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia.","authors":["Frangoul H","Altshuler D","Cappellini MD"]}],"source":"NCBI PubMed E-utilities","date_to":null,"returned":3,"date_from":null}},"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.01","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"registry","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.01/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.01","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.01","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_ecXwFZS4dlmOWWMf9oMxy","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.01","costPer":"request","priority":0,"asset":null,"unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Searches PubMed for biomedical and clinical research papers by free-text query, returning PMIDs, titles, authors, abstracts, MeSH terms, DOIs, and total hit counts.","exampleAgentPrompt":"Search PubMed for papers on CRISPR gene therapy for sickle cell disease published between 2020 and 2024, sorted by relevance, and give me the titles, authors, abstracts, and DOIs for the top results.","exampleUseCases":[{"title":"Clinical evidence review for treatment decision","prompt":"Search PubMed for randomized controlled trials on metformin versus SGLT2 inhibitors for type 2 diabetes published in the last three years, sorted by publication date, and summarize the abstracts and MeSH terms."},{"title":"Literature survey for a research paper","prompt":"I'm writing a review on neuroinflammation in Alzheimer's disease — can you search PubMed for the most relevant papers from 2018 to 2024 sorted by relevance, and pull back titles, authors, journals, and abstracts?"},{"title":"Finding papers for a specific first author","prompt":"Look up recent PubMed publications by Jennifer Doudna on base editing, sorted by first author, and return the PMIDs, titles, DOIs, and publication dates."}],"resultDescription":"Returns a total hit count for the query plus a list of matching papers, each containing PMID, title, author list, journal name, publication date, full abstract, MeSH terms, and DOI. Data is sourced from NCBI's public-domain federal database.","failureModes":["Query returns zero results if search terms are too specific or misspelled","Date range filters may exclude relevant preprints or ahead-of-print articles","Some older papers may lack DOIs or MeSH term annotations","Rate or usage limits may apply under high query volume","Abstract may be absent for some older or retracted articles"],"whenToPreferThis":"Use this endpoint when an agent needs structured, citation-quality biomedical literature data — including abstracts, MeSH terms, and DOIs — directly from the authoritative NIH PubMed database. Prefer it over general web search for medical/clinical queries because results are peer-reviewed, structured, and include rich metadata. Ideal for literature reviews, evidence synthesis, clinical research lookups, and any task requiring NCBI E-utilities data without managing API keys directly. The $0.01 per-call USDC pricing via x402 makes it accessible for autonomous agents.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-10-11T18:43:21.493Z","isFirstParty":false,"canonicalSlug":"pubmed-biomedical-literature-search-e64eb7b7"}