{"uid":"cap_PTsHqIsszAKJnA84mKEFM","slug":"longevitypulse-longevity-drug-intelligence-910565b7","name":"LongevityPulse Longevity Drug Intelligence","description":"Longevity drug / anti-aging pharmaceutical intelligence (rapamycin, metformin, acarbose, senolytics, SGLT2 inhibitors, GLP-1 agonists) for longevity and health agents. Evidence-graded analysis of drugs studied for healthspan, with human-vs-animal evidence and global availability. Health intelligence, not medical advice.","url":"https://longevitypulse.theaslangroupllc.com/api/longevity/longevity-drug","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"queryParams":{"type":"object","properties":{"drug":{"type":"string","description":"Drug name — e.g. \"rapamycin\" | \"metformin\" | \"acarbose\" | \"dasatinib\" | \"fisetin\" | \"senolytics\" | \"SGLT2 inhibitor\" | \"empagliflozin\" | \"GLP-1\" | \"semaglutide\""},"lang":{"type":"string","description":"en | es | fr | de | ja | zh | ko | pt | ar | hi (default: en)"}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"errors":{"type":"object","description":"Documented error responses, keyed by HTTP status code","additionalProperties":{"type":"object","required":["description"],"properties":{"example":{"type":"object"},"description":{"type":"string"}}}},"example":{"type":"object"}}}}},"responseSchema":{"type":"json","example":{"compound":"Rapamycin (Sirolimus)","drug_class":"mTOR inhibitor (macrolide)","fda_approved_for":"Organ transplant rejection prevention; certain cancers","longevity_use_case":"mTOR inhibition mimics caloric restriction — the most robust longevity intervention across species. Shown to extend lifespan in every animal model tested.","global_availability":{"prescription_status":"Prescription-only globally; Schedule F in US; available but off-label use varies by country"},"evidence_for_longevity":{"animal_evidence":{"lifespan_extension":"9-23% median lifespan extension in mice (ITP trials 2009, 2013, 2016) — even when started late in life"}}}},"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.2","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.2/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.2","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.2","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_HOzIs4ZYg1CT2WNDdloJU","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.2","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Returns evidence-graded pharmaceutical intelligence on longevity drugs (rapamycin, metformin, acarbose, senolytics, SGLT2 inhibitors, GLP-1 agonists) including human vs animal evidence and global availability.","exampleAgentPrompt":"What's the evidence grade for rapamycin as a longevity drug — does it have human clinical data or only animal studies, and is it available in the US?","exampleUseCases":[{"title":"Compare anti-aging drugs for personal research","prompt":"I'm trying to understand which longevity drugs have the strongest human evidence. Can you compare metformin, rapamycin, and senolytics for me — tell me which ones actually work in humans versus just in mice, and what the evidence grades are?"},{"title":"Build longevity protocol availability checker","prompt":"I need to know what pharmaceutical longevity interventions I can actually access where I live. Can you tell me which of the major anti-aging drugs like GLP-1 agonists, SGLT2 inhibitors, and acarbose are available in Canada, and what the research says about them for healthspan?"},{"title":"Evaluate emerging longevity compounds objectively","prompt":"There's a lot of hype around senolytics for aging. Give me the real evidence grade on whether they actually extend healthspan in humans, and how that compares to what we know about metformin and rapamycin from clinical studies."}],"resultDescription":"A structured evidence-graded profile for the requested longevity drug, including human vs animal study evidence, mechanism of action, healthspan and aging-related effects, evidence quality grade, and global availability information. Explicitly framed as health intelligence rather than medical advice.","failureModes":["Drug not found in database — returns empty or error if compound is not tracked","Ambiguous drug name — may return closest match or error if multiple compounds share a name","No human evidence available — returns animal-only data with appropriate grading","Unavailable in requested region — availability field may return null or restricted","Rate limiting or payment failure — 402 response if payment not processed correctly"],"whenToPreferThis":"Use this endpoint when an agent needs structured, evidence-graded intelligence specifically on pharmaceutical compounds studied for longevity or healthspan extension (rapamycin, metformin, senolytics, etc.), including differentiation between human and animal study data and global drug availability. Prefer over general medical databases when the focus is anti-aging/geroscience context rather than clinical treatment of disease.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T00:37:23.176Z","isFirstParty":false}