{"uid":"cap_N75lzkwCKib16J9EsuJFV","slug":"magent-chen-2013-kinetic-egfr-kegfr-calculator-406faf1b","name":"magent Chen 2013 Kinetic eGFR (KeGFR) Calculator","description":"Chen 2013 kinetic eGFR (KeGFR) from two plasma creatinines, hours between them, caller-assigned steady-state creatinine and corresponding eGFR/CrCl, and required max_delta_pcr_mg_dl_day (Chen usual default 1.5). KeGFR = (SSPCr * CrCl / MeanPCr) * (1 - 24*dPCr / (dTime_hours * MaxdPCr/Day)), clamped at 0 when that (1 - ratio) term is negative. Creatinine mg/dL only. Not a CKD-EPI result. Not a dialysis prescription. magent does not compute MDRD or CKD-EPI.","url":"https://api.magentlab.com/api/calc/kegfr","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["creatinine_1_mg_dl","creatinine_2_mg_dl","delta_hours","steady_state_creatinine_mg_dl","steady_state_egfr","max_delta_pcr_mg_dl_day"],"properties":{"delta_hours":{"type":"number","description":"Hours between creatinine_1 and creatinine_2 (1-72). Chen: endpoints <48-72 h apart."},"steady_state_egfr":{"type":"number","description":"Caller-assigned eGFR/CrCl in mL/min corresponding to steady_state_creatinine_mg_dl (5-200). magent does not compute MDRD or CKD-EPI."},"creatinine_1_mg_dl":{"type":"number","description":"First plasma creatinine in mg/dL (0.1-20). mg/dL only."},"creatinine_2_mg_dl":{"type":"number","description":"Second plasma creatinine in mg/dL (0.1-20). mg/dL only."},"max_delta_pcr_mg_dl_day":{"type":"number","description":"Maximum creatinine rise per day in mg/dL (0.5-3). Chen usual default 1.5. Required; magent does not omit it."},"steady_state_creatinine_mg_dl":{"type":"number","description":"Steady-state plasma creatinine in mg/dL (0.1-20) corresponding to steady_state_egfr. mg/dL only."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_NeRNnSwsdVUek2ZKdMVh-","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Computes the Chen 2013 kinetic estimated GFR (KeGFR) from two serial plasma creatinine values, time between them, and a caller-assigned steady-state creatinine with corresponding eGFR/CrCl.","exampleAgentPrompt":"A patient has a first creatinine of 1.2 mg/dL and a second of 2.1 mg/dL measured 18 hours later; their steady-state creatinine is 1.0 mg/dL with a corresponding eGFR of 75 mL/min and the max delta creatinine is 1.5 mg/dL/day — can you compute their kinetic eGFR using the Chen 2013 formula?","exampleUseCases":[{"title":"AKI nephrology consult kinetic GFR","prompt":"My patient's creatinine went from 0.9 to 1.8 mg/dL over 24 hours; their baseline creatinine is 0.9 mg/dL with a steady-state eGFR of 90 mL/min and we're using the standard Chen max delta of 1.5 mg/dL/day — what's their kinetic eGFR right now?"},{"title":"ICU drug dosing during acute creatinine rise","prompt":"For an ICU patient whose creatinine rose from 1.5 to 2.4 mg/dL in 12 hours, with a steady-state creatinine of 1.2 mg/dL and CrCl of 60 mL/min, can you calculate the Chen 2013 kinetic eGFR using a max delta of 1.5 mg/dL/day so I can adjust renally-dosed medications?"},{"title":"Serial creatinine monitoring in post-op patient","prompt":"My post-surgical patient had creatinines of 1.1 and 1.9 mg/dL taken 36 hours apart; their pre-op steady-state creatinine was 1.0 mg/dL with an eGFR of 80 mL/min — please compute the Chen kinetic eGFR with a max delta of 1.5 mg/dL/day."}],"resultDescription":"Returns a numeric kinetic eGFR value in mL/min calculated via the Chen 2013 formula: KeGFR = (SSPCr × CrCl / MeanPCr) × (1 − 24×dPCr / (dTime_hours × MaxdPCr/Day)), clamped to 0 if the bracketed term is negative. The result reflects estimated real-time kidney function when creatinine is not at steady state.","failureModes":["Missing required query parameters (creatinine_1_mg_dl, creatinine_2_mg_dl, delta_hours, steady_state_creatinine_mg_dl, steady_state_egfr, max_delta_pcr_mg_dl_day) returns an error","Creatinine values outside 0.1–20 mg/dL range may return validation error","delta_hours outside 1–72 hours may be rejected","steady_state_egfr outside 5–200 mL/min may fail validation","max_delta_pcr_mg_dl_day outside 0.5–3 may be rejected","Payment not provided or insufficient (x402 payment required at $0.005 USDC per call)"],"whenToPreferThis":"Use this endpoint when a patient's creatinine is acutely changing and a steady-state GFR assumption would overestimate or underestimate true kidney function. Prefer this over standard CKD-EPI or MDRD lookups when you have two serial creatinine measurements within 72 hours and want a kinetically-adjusted GFR. Do not use this for CKD staging, dialysis dosing prescription, or when you need CKD-EPI or MDRD specifically — those are not computed here.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-16T12:06:04.192Z","isFirstParty":false}