{"uid":"cap_LKm_vka1Mfr_NN4sJlpmb","slug":"med-halowerk-com-gene-crosswalk-e47f9ffc","name":"med.halowerk.com Gene Crosswalk","description":"Resolves a gene symbol or identifier and returns the corresponding identifiers across NCBI and Ensembl: the gene with its Entrez and Ensembl identifiers, the genomic location with assembly, the biotype, the description, and the transcripts with their protein products.","url":"https://med.halowerk.com/v1/gene-crosswalk","method":"POST","headers":{},"bodySchema":{"type":"object","properties":{"query":{"type":"string","maxLength":100,"minLength":2,"description":"Gene symbol like TP53, an Ensembl id like ENSG00000141510, or an Entrez gene id."},"species":{"type":"string","default":"homo_sapiens","maxLength":60,"description":"Ensembl species name. Required in practice — the same symbol exists in many species."},"include_transcripts":{"type":"boolean","default":true}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.006","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.006/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.006","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.006","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_c_Guu-tBMWjYzxqt7F462","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.006","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Resolves a gene symbol or identifier and returns cross-referenced identifiers (Entrez, Ensembl), genomic location, biotype, description, and associated transcripts with protein products.","exampleAgentPrompt":"Can you look up the gene BRCA2 and give me its Entrez and Ensembl identifiers, genomic location, biotype, and all its transcripts with protein products?","exampleUseCases":[{"title":"Cross-reference gene identifiers for pipeline","prompt":"I have a list of gene symbols like TP53 and EGFR — can you resolve each one to its Entrez and Ensembl IDs, genomic coordinates, and biotype so I can standardize them across databases?"},{"title":"Find transcripts for a gene of interest","prompt":"Can you look up the gene KRAS and return all its transcript isoforms along with their associated protein products?"},{"title":"Validate gene annotation in research workflow","prompt":"I need to confirm the official description, chromosomal assembly location, and biotype for the gene PTEN — can you pull that from NCBI and Ensembl?"}],"resultDescription":"Returns a structured record for the resolved gene including: Entrez gene ID, Ensembl gene ID, genomic location with assembly version, biotype (e.g. protein-coding, lncRNA), official gene description, and a list of transcripts each with their corresponding protein product identifiers.","failureModes":["Unrecognized gene symbol returns an error or empty result","Ambiguous identifier matching multiple genes may return unexpected results","Gene identifiers not present in NCBI or Ensembl databases return no data","Deprecated or retired gene symbols may fail to resolve","Network or upstream database unavailability causes timeout"],"whenToPreferThis":"Use this endpoint when you need to cross-reference gene identifiers between NCBI (Entrez) and Ensembl databases in a single call, especially when you also need genomic coordinates, biotype, official description, and transcript-to-protein mappings. Prefer it over manual database lookups or separate API calls to NCBI and Ensembl when building bioinformatics pipelines, annotation tools, or research workflows that require normalized gene metadata.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-15T06:46:21.390Z","isFirstParty":false}