{"uid":"cap_KxlxnkhPwBmKL7By5iVpQ","slug":"leibovich-2018-rcc-prognostic-score-calculator-7071ebb9","name":"Leibovich 2018 RCC Prognostic Score Calculator","description":"Leibovich 2018 histology-specific RCC models after surgery. Required histology clear_cell, papillary, or chromophobe. ccRCC PFS points (2010 TNM): t1a/t1b/t2a 0, t2b 2, t3a-t3c 3, t4 4; nx/n0 0, n1 2; size ≥10 cm 1; grade 1-2 0, 3 1, 4 3; necrosis 2; max 12; risk low 0-2, intermediate 3-5, high ≥6. Papillary and chromophobe return the 2018 three PFS groups (score 0-2). Not SSIGN. Not Leibovich 2003. magent does not stage or read pathology. Not a diagnosis. Not a medical device.","url":"https://api.magentlab.com/api/calc/leibovich_2018","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["histology","t_stage","n_stage","tumor_size_cm","nuclear_grade","necrosis"],"properties":{"n_stage":{"enum":["nx","n0","n1"],"type":"string","description":"2010 pathologic N as assigned by the caller (Leibovich 2018). nx or n0 scores 0 on ccRCC; n1 scores 2. Not n2 (2002 N). magent does not stage nodes."},"t_stage":{"enum":["t1a","t1b","t2a","t2b","t3a","t3b","t3c","t4"],"type":"string","description":"2010 pathologic T as assigned by the caller (Leibovich 2018). t1a, t1b, t2a, t2b, t3a, t3b, t3c, or t4. Not 1997/2002 T without a/b substages. magent does not stage the tumor."},"necrosis":{"type":"boolean","description":"Histologic tumor necrosis as assigned by the caller (Leibovich 2018). true scores 2 on ccRCC. magent does not read slides."},"histology":{"enum":["clear_cell","papillary","chromophobe"],"type":"string","description":"Surgical histology as assigned by the caller (Leibovich 2018). clear_cell, papillary, or chromophobe. Not collecting-duct or unclassified. magent does not read slides."},"nuclear_grade":{"type":"integer","description":"Nuclear grade 1-4 as assigned by the caller (Leibovich 2018). On ccRCC, 1-2 score 0; 3 scores 1; 4 scores 3. Integer 1-4 only; reject 0, 5, 1.5, and roman I. magent does not read slides."},"tumor_size_cm":{"type":"number","description":"Maximum tumor size in cm as assigned by the caller (Leibovich 2018). Unrounded; 10.0 cm or greater scores 1 on ccRCC. Magent clamp 0.1-30, not a published range. magent does not measure the tumor."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_nIdFTMiY6e6xH2jAQtBwW","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Computes the Leibovich 2018 histology-specific prognostic score and PFS risk group for clear cell, papillary, or chromophobe renal cell carcinoma after surgery.","exampleAgentPrompt":"Calculate the Leibovich 2018 score for a patient with clear cell RCC: T stage t3a, N stage n0, tumor size 7.5 cm, nuclear grade 3, and no histologic necrosis.","exampleUseCases":[{"title":"Post-nephrectomy ccRCC risk stratification","prompt":"I have a clear cell RCC patient post-nephrectomy: T stage t2b, N1, tumor 11 cm, nuclear grade 4, with necrosis present — what is their Leibovich 2018 score and risk group?"},{"title":"Papillary RCC follow-up planning","prompt":"Can you get the Leibovich 2018 PFS risk group for a papillary RCC patient with T stage t1b, N0, tumor 4.2 cm, nuclear grade 2, and no necrosis?"},{"title":"Chromophobe RCC surveillance categorization","prompt":"Run the Leibovich 2018 calculator for chromophobe RCC: T stage t3a, N stage nx, tumor size 6.0 cm, nuclear grade 3, necrosis absent — what risk tier does this patient fall into?"}],"resultDescription":"Returns the Leibovich 2018 prognostic score (integer, max 12 for ccRCC) and the corresponding PFS risk group (low, intermediate, or high for clear cell; three groups for papillary and chromophobe), based on the caller-supplied pathologic parameters.","failureModes":["Unsupported histology (e.g. collecting-duct or unclassified RCC) returns an error — only clear_cell, papillary, chromophobe accepted","Invalid T stage (e.g. pre-2010 stages without a/b substages) will be rejected","Nuclear grade outside 1–4 integer range (e.g. 0, 5, or fractional values) returns validation error","Tumor size outside clamped range (0.1–30 cm) may be rejected or clamped","Missing required query parameters returns a 400-level error"],"whenToPreferThis":"Use this endpoint when you need the Leibovich 2018 histology-specific prognostic model (not SSIGN, not Leibovich 2003) for clear cell, papillary, or chromophobe RCC after surgical resection, with caller-supplied 2010 TNM staging, nuclear grade, and necrosis status. It is the correct tool when downstream logic requires the validated three-tier PFS risk group from the 2018 Mayo Clinic publication.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T13:07:20.701Z","isFirstParty":false}