{"uid":"cap_Jwjw0OMlnU2YpKUxkZBFN","slug":"gillmore-2018-attr-cardiac-staging-calculator-7529852f","name":"Gillmore 2018 ATTR Cardiac Staging Calculator","description":"Gillmore 2018 NAC ATTR cardiac staging from NT-proBNP (ng/L) and caller-assigned eGFR. Stage I: NT-proBNP <=3000 and eGFR >=45. Stage III: NT-proBNP >3000 and eGFR <45. Stage II: exactly one of those two adverse cut points. Returns gillmore_stage 1/2/3. ATTRwt and ATTRv. Not Mayo AL amyloid staging. Not NYHA. Not a treatment order. magent does not compute MDRD or CKD-EPI.","url":"https://api.magentlab.com/api/calc/gillmore","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["nt_probnp_ng_l","egfr_ml_min_1_73m2"],"properties":{"nt_probnp_ng_l":{"type":"number","description":"NT-proBNP in ng/L (10-100000), same numeric value as pg/mL. Gillmore 2018 Stage I requires <= 3000; Stage III when > 3000. magent does not assay NT-proBNP."},"egfr_ml_min_1_73m2":{"type":"number","description":"Caller-assigned eGFR in mL/min/1.73m² (5-200). Gillmore 2018 Stage I requires >= 45; Stage III when < 45. magent does not compute MDRD or CKD-EPI."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_fxONAZr9-5B_6Zvn_OTp2","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Computes the Gillmore 2018 cardiac staging (I, II, or III) for ATTR amyloidosis (ATTRwt and ATTRv) from NT-proBNP and eGFR values","exampleAgentPrompt":"My ATTR amyloidosis patient has an NT-proBNP of 4200 ng/L and a pre-calculated eGFR of 38 mL/min/1.73m² — what is their Gillmore 2018 cardiac stage?","exampleUseCases":[{"title":"Staging newly diagnosed ATTRwt patient","prompt":"I have a new wild-type ATTR amyloidosis patient with NT-proBNP of 2800 ng/L and eGFR of 52 mL/min/1.73m² — give me their Gillmore 2018 cardiac stage."},{"title":"Monitoring ATTRv patient disease progression","prompt":"My hereditary ATTR patient's latest labs show NT-proBNP of 5100 ng/L and eGFR of 41 mL/min/1.73m² — what Gillmore 2018 stage are they in now?"},{"title":"Pre-treatment cardiac risk stratification","prompt":"Before starting tafamidis, I need the Gillmore 2018 ATTR cardiac stage for a patient with NT-proBNP 1500 ng/L and eGFR 60 mL/min/1.73m²."}],"resultDescription":"Returns a gillmore_stage value of 1, 2, or 3. Stage I: NT-proBNP ≤3000 ng/L AND eGFR ≥45. Stage III: NT-proBNP >3000 ng/L AND eGFR <45. Stage II: exactly one of those two adverse thresholds met. No treatment recommendations or additional computed values are included.","failureModes":["NT-proBNP outside range 10–100000 ng/L returns a validation error","eGFR outside range 5–200 mL/min/1.73m² returns a validation error","Missing required query parameters returns an error response","This endpoint does not compute eGFR — caller must supply a pre-calculated eGFR value","Passing AL amyloid patients will not yield a clinically valid result as this is ATTR-specific staging"],"whenToPreferThis":"Use this endpoint when you need to apply the Gillmore 2018 NAC ATTR-specific cardiac staging system (Stage I/II/III) for ATTRwt or ATTRv patients based on NT-proBNP and eGFR. Do not use for AL amyloidosis (Mayo staging), NYHA classification, or when eGFR has not yet been calculated — this endpoint requires a pre-computed eGFR value and does not run MDRD or CKD-EPI itself.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T19:00:12.140Z","isFirstParty":false}