{"uid":"cap_JgU_wAPd_K-AJqR0RjlSG","slug":"sirs-criteria-calculator-bone-1992-accp-sccm-9250da43","name":"SIRS Criteria Calculator (Bone 1992 ACCP/SCCM)","description":"Deterministic published-formula arithmetic plus ICD-10-CM, RxNorm, and LOINC. Pay in USDC on Base via x402.","url":"https://api.magentlab.com/api/calc/sirs?utm_source=zero.xyz","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["temperature_c","heart_rate_bpm","respiratory_rate"],"properties":{"wbc_ul":{"type":"number","description":"WBC in cells/µL (same as cells/mm^3). Provide wbc_k_ul or wbc_ul. Range 10-500000. >12000 or <4000 scores 1 (12000 and 4000 do not)."},"wbc_k_ul":{"type":"number","description":"WBC in 10^3/µL (same as 10^9/L). Provide wbc_k_ul or wbc_ul. Range 0.01-500. >12000 or <4000 per µL scores 1."},"paco2_mm_hg":{"type":"number","description":"Arterial PaCO2 in mm Hg (8-80) when provided. Omitted uses respiratory rate only. <32 scores the respiratory criterion (32 does not)."},"band_percent":{"type":"number","description":"Immature bands as a percent of WBC (0-100) when provided. Omitted does not use bands. >10 scores the WBC criterion (10 does not)."},"temperature_c":{"type":"number","description":"Temperature in °C (30.0-45.0). >38 or <36 scores 1 (38.0 and 36.0 do not)."},"heart_rate_bpm":{"type":"integer","description":"Heart rate in beats/min (integer 30-220). >90 scores 1 (90 does not)."},"respiratory_rate":{"type":"integer","description":"Respiratory rate in breaths/min (integer 4-80). >20 scores 1 for the respiratory criterion (20 does not). Optional paco2_mm_hg <32 also meets this criterion."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":{"type":"json","example":{"path":"/api/calc/sirs","count":2,"items":[{"formula":"sirs","citation":{"id":"bone-1992","doi":"10.1378/chest.101.6.1644","title":"Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis","source":"Chest. 1992;101(6):1644-1655","authors":"Bone RC, Balk RA, Cerra FB, et al."},"max_score":4,"components":[{"value":37,"factor":"temperature","points":0,"present":false},{"value":80,"factor":"heart_rate_gt_90","points":0,"present":false},{"value":16,"factor":"respiratory","points":0,"present":false},{"value":8000,"factor":"wbc","points":0,"present":false}],"disclaimer":"Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.","wbc_per_ul":8000,"sirs_present":false,"temperature_c":37,"heart_rate_bpm":80,"respiratory_rate":16,"sirs_criteria_met":0,"formula_expression":"SIRS present iff >=2 of 4: (temperature_c >38 or <36) + (heart_rate_bpm >90) + (respiratory_rate >20 or paco2_mm_hg <32) + (wbc_per_ul >12000 or <4000 or band_percent >10); each 1; max 4"},{"formula":"sirs","citation":{"id":"bone-1992","doi":"10.1378/chest.101.6.1644","title":"Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis","source":"Chest. 1992;101(6):1644-1655","authors":"Bone RC, Balk RA, Cerra FB, et al."},"max_score":4,"components":[{"value":37,"factor":"temperature","points":0,"present":false},{"value":80,"factor":"heart_rate_gt_90","points":0,"present":false},{"value":16,"factor":"respiratory","points":0,"present":false},{"value":8000,"factor":"wbc","points":0,"present":false}],"disclaimer":"Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.","wbc_per_ul":8000,"sirs_present":false,"temperature_c":37,"heart_rate_bpm":80,"respiratory_rate":16,"sirs_criteria_met":0,"formula_expression":"SIRS present iff >=2 of 4: (temperature_c >38 or <36) + (heart_rate_bpm >90) + (respiratory_rate >20 or paco2_mm_hg <32) + (wbc_per_ul >12000 or <4000 or band_percent >10); each 1; max 4"}]}},"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_Gj1Xi_o-9vSHgoyGGx4hR","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Calculates Systemic Inflammatory Response Syndrome (SIRS) score using the classic Bone 1992 ACCP/SCCM four-criterion definition, returning whether SIRS is present (≥2 of 4 criteria met).","exampleAgentPrompt":"Does this patient meet SIRS criteria? Temperature is 38.5 °C, heart rate is 102 bpm, respiratory rate is 22 breaths/min, and WBC is 14,500 per µL.","exampleUseCases":[{"title":"ICU sepsis screening from chart values","prompt":"I'm reviewing an ICU patient: temp 35.8 °C, heart rate 95 bpm, respiratory rate 18, and WBC 3,200 per µL. How many SIRS criteria are met and is SIRS present?"},{"title":"ED triage SIRS check with PaCO2","prompt":"Patient in the ED has temperature 39.1 °C, heart rate 110 bpm, respiratory rate 24 breaths/min, and arterial PaCO2 of 29 mm Hg — do they meet Bone 1992 SIRS criteria?"},{"title":"Automated chart review with band count","prompt":"Run SIRS scoring on this CBC and vitals: temperature 37.2 °C, heart rate 88 bpm, respiratory rate 19, WBC 11,000 per µL, and bands at 13%. Is SIRS positive?"}],"resultDescription":"Returns a structured object indicating whether SIRS is present (true/false), the total number of SIRS criteria met (0–4), and the individual pass/fail result for each of the four criteria: temperature, heart rate, respiratory/PaCO2, and WBC/bands.","failureModes":["Missing required parameters (temperature_c, heart_rate_bpm, respiratory_rate) returns a 400 error","Temperature out of range 30.0–45.0 °C rejected","Heart rate outside 30–220 bpm rejected","Respiratory rate outside 4–80 rejected","WBC value out of accepted range rejected","Payment not included or invalid returns 402 Payment Required","Providing both wbc_ul and wbc_k_ul may cause ambiguity — prefer one unit"],"whenToPreferThis":"Use this endpoint when you need a fast, deterministic, citation-backed SIRS calculation per the original Bone 1992 ACCP/SCCM definition. Prefer it over manual rule-coding when building clinical decision support, sepsis screening pipelines, or automated chart review tools. Note this is NOT Sepsis-3, qSOFA, or SOFA — choose it explicitly when the older SIRS framework is required (e.g., for legacy protocols, research replication, or insurance/billing workflows referencing Bone 1992).","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-10-12T00:42:01.433Z","isFirstParty":false,"canonicalSlug":"sirs-criteria-calculator-bone-1992-accp-sccm-9250da43"}