{"uid":"cap_HXTbORyNwjDYZH-Ppir0k","slug":"sitecheck-fda-adverse-events-lookup-eb57b879","name":"SiteCheck FDA Adverse Events Lookup","description":"The most reported adverse reactions to a drug in FDA's FAERS database: counts, total reports and the share that were serious. Reports are voluntary and show association, not proof of cause. Source: openFDA. Information only, not medical advice.","url":"https://api.sitecheck-api.workers.dev/api/fda/adverse-events?utm_source=zero.xyz","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET"],"type":"string"},"queryParams":{"type":"object","required":["drug"],"properties":{"drug":{"type":"string","description":"Generic drug name, e.g. ibuprofen"},"limit":{"type":"string","description":"Top reactions, 1 to 25 (default 10)"}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":{"type":"json","example":{"drug":"ibuprofen","source":"https://api.fda.gov/drug/event.json","checkedAt":"2026-10-14T07:00:32.179Z","reactions":[{"reports":27383,"reaction":"DRUG INEFFECTIVE"},{"reports":19493,"reaction":"PAIN"},{"reports":18755,"reaction":"FATIGUE"}],"disclaimer":"Information only, not medical advice.","attribution":"openFDA (FAERS, reports are not proof of cause)","totalReports":283534,"seriousReports":178866,"seriousSharePct":63.1}},"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.002","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.002/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.002","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.002","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_xVyTzmUu5kFdPwbxy4DP0","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.002","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Returns the top adverse event reactions reported to the FDA for a given drug, sourced from the openFDA FAERS database.","exampleAgentPrompt":"What are the top 10 adverse events reported to the FDA for ibuprofen? Pull the data from the FDA FAERS database and show me how many reports are serious.","exampleUseCases":[{"title":"Drug safety research for patients","prompt":"Can you look up the most common adverse reactions reported to the FDA for metformin? Show me the top 15 and tell me what share of reports were considered serious."},{"title":"Pharmacist drug comparison workflow","prompt":"What are the top adverse events on record with the FDA for warfarin? I want to see the reaction names and how many reports each one has."},{"title":"Healthcare compliance risk screening","prompt":"Pull FDA adverse event data for atorvastatin — give me the top 5 reactions, total reports, and the percentage that were flagged as serious."}],"resultDescription":"A JSON object containing the queried drug name, the openFDA source URL, a timestamp, an ordered list of up to 25 adverse reactions each with their report count, total report count, serious report count, serious share percentage, and disclaimers about data provenance (FAERS, not proof of causation).","failureModes":["Drug name not found in FAERS — returns empty reactions array or error","Invalid or missing 'drug' query parameter — likely 400 or error response","Limit parameter outside 1–25 range — may default or return error","OpenFDA upstream API unavailable — proxy error or timeout","Misspelled drug name yields no results or unexpected matches"],"whenToPreferThis":"Use this endpoint when you need quick, aggregated FDA FAERS adverse event statistics for a named drug without building your own openFDA integration. It's ideal for AI agents performing drug safety lookups, pharmacovigilance summaries, or healthcare compliance checks. Prefer it over direct openFDA calls when you want pay-per-call simplicity with pre-aggregated reaction counts and seriousness metrics already computed.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-10-28T06:45:41.334Z","isFirstParty":false,"canonicalSlug":"sitecheck-fda-adverse-events-lookup-eb57b879"}