{"uid":"cap_G_zpXnJe32bhCP_2e7Ioo","slug":"magent-myxedema-coma-score-popoveniuc-2014-1043ff73","name":"Magent Myxedema Coma Score (Popoveniuc 2014)","description":"Popoveniuc 2014 myxedema coma points from caller-assigned bands: thermoregulatory 0/10/20; CNS 0/10/15/20/30; GI 0/5/15/20; precipitant 10; bradycardia 0/10/20/30 plus other EKG 10, effusion 10, pulmonary edema 15, cardiomegaly 15, hypotension 20; five metabolic flags 10 each. Max 230. ≥60 potentially diagnostic; 45–59 at risk. Not a diagnosis or thyroid-hormone order. magent does not measure temperature, GCS, or labs.","url":"https://api.magentlab.com/api/calc/myxedema_coma","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["thermoregulatory","cns_effects","gastrointestinal","precipitating_event","bradycardia","other_ekg_changes","pericardial_pleural_effusion","pulmonary_edema","cardiomegaly","hypotension","hyponatremia","hypoglycemia","hypoxemia","hypercarbia","decreased_gfr"],"properties":{"hypoxemia":{"type":"boolean","description":"Hypoxemia as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not measure oxygen."},"bradycardia":{"enum":["absent","50_to_59","40_to_49","lt_40"],"type":"string","description":"Caller-assigned Popoveniuc 2014 bradycardia band. absent scores 0; 50_to_59 (heart rate 50–59) scores 10; 40_to_49 scores 20; lt_40 (<40) scores 30. magent does not measure heart rate."},"cns_effects":{"enum":["absent","somnolent_lethargic","obtunded","stupor","coma_seizures"],"type":"string","description":"Caller-assigned Popoveniuc 2014 central-nervous-system band. absent scores 0; somnolent_lethargic 10; obtunded 15; stupor 20; coma_seizures 30. magent does not compute GCS or examine the patient."},"hypercarbia":{"type":"boolean","description":"Hypercarbia as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not measure carbon dioxide."},"hypotension":{"type":"boolean","description":"Hypotension or shock as assigned by the caller (true or false). Popoveniuc 2014: true → 20. magent does not measure blood pressure."},"cardiomegaly":{"type":"boolean","description":"Cardiomegaly as assigned by the caller (true or false). Popoveniuc 2014: true → 15. magent does not interpret imaging."},"hypoglycemia":{"type":"boolean","description":"Hypoglycemia as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not measure glucose."},"hyponatremia":{"type":"boolean","description":"Hyponatremia as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not measure sodium."},"decreased_gfr":{"type":"boolean","description":"Decrease in glomerular filtration rate as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not compute GFR."},"pulmonary_edema":{"type":"boolean","description":"Pulmonary edema as assigned by the caller (true or false). Popoveniuc 2014: true → 15. magent does not interpret imaging."},"gastrointestinal":{"enum":["absent","anorexia_pain_constipation","decreased_motility","paralytic_ileus"],"type":"string","description":"Caller-assigned Popoveniuc 2014 gastrointestinal band. absent scores 0; anorexia_pain_constipation (anorexia, abdominal pain, or constipation) scores 5; decreased_motility 15; paralytic_ileus 20. magent does not examine the patient."},"thermoregulatory":{"enum":["gt_35","32_to_35","lt_32"],"type":"string","description":"Caller-assigned Popoveniuc 2014 thermoregulatory band. gt_35 (>35 °C) scores 0; 32_to_35 (32–35 °C) scores 10; lt_32 (<32 °C) scores 20. magent does not measure temperature."},"other_ekg_changes":{"type":"boolean","description":"Other electrocardiogram changes as assigned by the caller (true or false): QT prolongation, low voltage, bundle-branch block, nonspecific ST-T changes, or heart block (Popoveniuc 2014). true → 10. magent does not read an ECG."},"precipitating_event":{"type":"boolean","description":"Precipitating event as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not take a history."},"pericardial_pleural_effusion":{"type":"boolean","description":"Pericardial or pleural effusion as assigned by the caller (true or false). Popoveniuc 2014: true → 10. magent does not interpret imaging."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_I1HTEO3oWcLaGKxlWnq3a","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Calculates the Popoveniuc 2014 myxedema coma diagnostic score from caller-supplied clinical bands across thermoregulatory, CNS, GI, cardiovascular, and metabolic domains (max 230 points).","exampleAgentPrompt":"Score this patient for myxedema coma using the Popoveniuc 2014 criteria: temperature band is thermoregulatory 20 points (hypothermia present), CNS is obtunded, GI effects are absent, there was a precipitating event, bradycardia is in the 40-to-49 range, no other EKG changes, no effusion, no pulmonary edema, no cardiomegaly, hypotension is present, hyponatremia is true, hypoglycemia is false, hypoxemia is true, hypercarbia is false, and GFR is decreased.","exampleUseCases":[{"title":"ED triage for hypothyroid emergency","prompt":"I have an ED patient with severe hypothermia, stuporous mental status, a precipitating event (infection), heart rate of 42, hypotension, and hyponatremia — can you run the Popoveniuc myxedema coma score? CNS is stupor, GI effects absent, no effusion, no pulmonary edema, no cardiomegaly, no other EKG changes, hypoglycemia false, hypoxemia false, hypercarbia false, GFR not decreased."},{"title":"ICU hypothyroid coma risk stratification","prompt":"Score this ICU patient on the Popoveniuc 2014 myxedema coma scale: thermoregulatory band is 10, CNS is coma_seizures, GI is 15, precipitating event present, bradycardia lt_40, other EKG changes yes, pericardial effusion yes, pulmonary edema yes, cardiomegaly yes, hypotension yes, hyponatremia true, hypoglycemia true, hypoxemia true, hypercarbia true, decreased GFR true."},{"title":"Outpatient consult myxedema screening","prompt":"Can you calculate the Popoveniuc myxedema coma score for a patient who is somnolent and lethargic, has mild GI symptoms (band 5), no precipitating event, heart rate 52 so bradycardia band 50_to_59, no EKG changes, no effusion, no pulmonary edema, no cardiomegaly, no hypotension, no thermoregulatory dysfunction, and all metabolic flags — hyponatremia, hypoglycemia, hypoxemia, hypercarbia, decreased GFR — are false?"}],"resultDescription":"Returns a numeric myxedema coma score (0–230) computed from the caller-supplied clinical bands and boolean flags. The score is interpreted as: ≥60 potentially diagnostic for myxedema coma, 45–59 at risk. The endpoint does not perform any measurement, lab interpretation, or imaging analysis — all inputs must be pre-assigned by the caller. The result is a decision-support value only and does not constitute a diagnosis.","failureModes":["Missing required query parameters returns a validation error","Invalid enum values for banded fields (e.g. unrecognized bradycardia band) return an error","Boolean fields supplied as non-boolean strings may cause schema rejection","Payment failure (x402) if USDC balance is insufficient — call not processed","Score returned is only as accurate as caller-supplied inputs; no measurement or validation of clinical values is performed"],"whenToPreferThis":"Use this endpoint when you need a structured, reproducible computation of the Popoveniuc 2014 myxedema coma score and all required clinical bands and flags have already been determined by a clinician or upstream system. It is the right choice for clinical decision-support pipelines in emergency, ICU, or endocrine settings where the scoring arithmetic needs to be automated. Do not use it to measure vital signs, interpret labs, or diagnose — those inputs must come from the caller.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T07:07:37.891Z","isFirstParty":false}