{"uid":"cap_Cgzv-3MDTL-z1Z0KNFvwC","slug":"federal-register-pharma-regulatory-changes-feed-fa76271f","name":"Federal Register Pharma Regulatory Changes Feed","description":"Federal Register final & proposed rules affecting prescription drugs & biologics (Food And Drug Administration) since a timestamp — covering drug, biologic, nda, anda, clinical — each scored 1-10 for compliance impact, with effective dates and primary-source links.","url":"https://oracles-production.up.railway.app/v1/reg-pharma/changes","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET"],"type":"string"},"queryParams":{"type":"object","properties":{"limit":{"type":"integer","maximum":500,"minimum":1},"since":{"type":"string","format":"date-time","description":"Only changes detected after this ISO-8601 instant"},"min_significance":{"type":"integer","maximum":10,"minimum":1,"description":"Keep only changes scored at least this"}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object","properties":{"count":{"type":"integer"},"source":{"type":"string"},"changes":{"type":"array","items":{"type":"object","properties":{"type":{"type":"string"},"title":{"type":"string"},"detail":{"type":"object"},"summary":{"type":"string"},"entityId":{"type":"string"},"sourceUrl":{"type":["string","null"],"description":"Primary-source link for verification"},"detectedAt":{"type":"string","format":"date-time"},"significance":{"type":"integer","maximum":10,"minimum":1},"effectiveDate":{"type":["string","null"]}}}}}}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.05","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.05/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.05","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.05","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_ZUGT3Niyc3ACnb7DilJNF","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.05","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Returns Federal Register final and proposed rules for prescription drugs and biologics since a given timestamp, each scored 1-10 for compliance impact with effective dates and primary-source links.","exampleAgentPrompt":"Pull all Federal Register prescription drug and biologics rule changes since 2025-01-01T00:00:00Z that have a compliance significance score of at least 7, and show me the titles, effective dates, and source links.","exampleUseCases":null,"resultDescription":"A JSON object containing a count of matching changes and an array of rule-change records, each with: title, type (final/proposed), a 1-10 significance score, summary text, effective date, detected-at timestamp, entity ID, and a primary-source URL linking to the official Federal Register entry.","failureModes":["Invalid or missing 'since' date format returns a 400 validation error","'min_significance' outside 1-10 range returns a 400 error","'limit' outside 1-500 range returns a 400 error","No matching rules in the time window returns an empty changes array with count 0","Payment not included or insufficient returns 402 Payment Required","Upstream Federal Register API unavailable may return 503 or empty results","Very broad time ranges with no limit may return large payloads or timeout"],"whenToPreferThis":"Use this endpoint when you need a structured, scored, filtered feed of pharmaceutical regulatory changes from the Federal Register — especially when compliance impact scoring and effective dates are needed for automated monitoring or alerting. Prefer over manually scraping federalregister.gov or using a general web search when you need machine-readable, date-bounded, significance-filtered results for prescription drugs and biologics specifically.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-15T12:44:12.755Z","isFirstParty":false}