{"uid":"cap_AbxKQ9Rf5b8rlnHTAlc79","slug":"sic-sepsis-induced-coagulopathy-score-calculator-f38c1df7","name":"SIC (Sepsis-Induced Coagulopathy) Score Calculator","description":"Iba 2017 SIC (Table 3; max 6). platelets_10e9_l >=150=0, <150 and >=100=1, <100=2. inr <=1.2=0, >1.2 and <=1.4=1, >1.4=2. sofa_four_items is the caller-assigned respiratory+cardiovascular+hepatic+renal SOFA sum (0-16; not coagulation, not CNS): 0=0, 1=1, >=2=2 (cap 2). sic true iff score >=4 and platelet_pts+inr_pts >=3. Not a sepsis or DIC diagnosis. Not ISTH overt DIC. Not JAAM-DIC. magent does not start anticoagulants.","url":"https://api.magentlab.com/api/calc/sic","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["platelets_10e9_l","inr","sofa_four_items"],"properties":{"inr":{"type":"number","description":"INR (0.8-10). <=1.2 scores 0; >1.2 and <=1.4 scores 1; >1.4 scores 2. 1.2 scores 0; 1.4 scores 1; 1.41 scores 2 (Iba 2017 Table 3)."},"sofa_four_items":{"type":"integer","description":"Caller-assigned sum of respiratory + cardiovascular + hepatic + renal SOFA only (integer 0-16). Do not include coagulation or CNS. 0 scores 0; 1 scores 1; >=2 scores 2 (cap 2). 2 and 16 both score 2 (Iba 2017 Table 3). magent does not compute those organ scores."},"platelets_10e9_l":{"type":"number","description":"Platelet count ×10^9/L (1-2000). >=150 scores 0; <150 and >=100 scores 1; <100 scores 2. 150 scores 0; 100 scores 1; 99 scores 2 (Iba 2017 Table 3)."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_dTfamte0R4UzjvhQx-b8f","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Computes the Iba 2017 Sepsis-Induced Coagulopathy (SIC) score from platelet count, INR, and partial SOFA score, returning total score and SIC diagnosis flag","exampleAgentPrompt":"Can you calculate the SIC score for my ICU patient who has a platelet count of 95 ×10⁹/L, an INR of 1.5, and a combined respiratory plus cardiovascular plus hepatic plus renal SOFA score of 4? I need to know if they meet Iba 2017 SIC criteria.","exampleUseCases":[{"title":"ICU sepsis coagulopathy screening","prompt":"My sepsis patient in the ICU has platelets at 110, an INR of 1.35, and their respiratory, cardiovascular, hepatic, and renal SOFA scores add up to 3 — can you run the SIC score and tell me if they're positive?"},{"title":"Bedside SIC check during morning rounds","prompt":"Quick SIC score check: platelets are 180 ×10⁹/L, INR is 1.1, and the four-organ SOFA sum is 2 — are they SIC positive by Iba 2017 criteria?"},{"title":"Research cohort SIC classification","prompt":"I need to classify a study patient: platelet count 88 ×10⁹/L, INR 1.6, and their combined respiratory plus cardiovascular plus hepatic plus renal SOFA is 5. What is their SIC score and do they meet the threshold?"}],"resultDescription":"Returns the total SIC score (0–6), individual component points for platelets (0–2), INR (0–2), and the capped SOFA contribution (0–2), plus a boolean SIC-positive flag (true if total score ≥4 AND platelet_pts + INR_pts ≥3). Does not initiate treatment or provide a DIC or sepsis diagnosis.","failureModes":["Missing required query parameters (platelets_10e9_l, inr, sofa_four_items) returns a 400 error","Out-of-range platelet value (outside 1–2000) may return a validation error","Out-of-range INR (outside 0.8–10) may return a validation error","sofa_four_items outside integer range 0–16 returns a validation error","Payment not provided or invalid x402 payment header returns a 402 Payment Required","Network timeout if the service is temporarily unavailable"],"whenToPreferThis":"Use this endpoint when you need to apply the Iba 2017 SIC criteria specifically — distinct from ISTH overt DIC, JAAM-DIC, and general sepsis diagnosis. Ideal when you have platelet count, INR, and have already computed the four-organ (respiratory, cardiovascular, hepatic, renal) SOFA subscores and need a fast, rule-based SIC classification without coagulation or CNS SOFA components.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T19:01:40.875Z","isFirstParty":false}