{"uid":"cap_7_I8pzhrtT3m3xK729kz3","slug":"sitecheck-health-travel-reactome-biological-pathways-ed11c14b","name":"SiteCheck Health & Travel – Reactome Biological Pathways","description":"Reactome curated human biological pathways matching a term (Reactome ContentService, CC BY 4.0): stable ID, pathway name, whether it is a disease pathway and a short summary. Human pathways only. Up to 20 per call.","url":"https://api.healthtravel-api.workers.dev/api/health/reactome-biological-paths?utm_source=zero.xyz","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET"],"type":"string"},"queryParams":{"type":"object","required":["q"],"properties":{"q":{"type":"string","description":"Search words, letters, digits and spaces, 2 to 60 characters"},"max":{"type":"string","description":"How many pathways, 1 to 20 (default 5)"}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.002","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.002/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.002","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.002","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_t9Y2ODP51jlIUUJ7aP6wh","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.002","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Returns Reactome-curated human biological pathways matching a search term, including stable ID, pathway name, disease flag, and short summary (up to 20 results).","exampleAgentPrompt":"Search Reactome for human biological pathways related to 'insulin signaling' and give me up to 10 results, including whether any are disease pathways.","exampleUseCases":[{"title":"Gene function research for lab scientist","prompt":"Find me all Reactome human pathways associated with BRCA1 — I want up to 15 results so I can see which ones are flagged as disease pathways."},{"title":"Drug target pathway discovery","prompt":"Search Reactome for human biological pathways involving 'apoptosis' and return the top 10, including their stable IDs and summaries so I can assess them for drug targeting."},{"title":"Immune response pathway lookup","prompt":"Can you pull Reactome pathways for 'innate immune response' in humans? Give me up to 20 and flag which ones are disease-related."}],"resultDescription":"A list of up to 20 Reactome-curated human biological pathways matching the search term. Each result includes the stable pathway ID (e.g. R-HSA-XXXXXX), the pathway name, a boolean or flag indicating whether it is a disease pathway, and a short descriptive summary of the pathway.","failureModes":["Query string shorter than 2 or longer than 60 characters returns a validation error","No pathways found for an obscure or misspelled term returns an empty result set","Max parameter outside 1–20 range may be rejected or clamped","Non-human pathway terms may return zero results since only human pathways are included","Reactome ContentService upstream unavailability causes a 5xx error"],"whenToPreferThis":"Choose this endpoint when you need curated, authoritative human biological pathway data from Reactome with disease annotations, particularly for bioinformatics workflows, gene function research, or drug target discovery. It is ideal when you need pathway stable IDs and summaries for up to 20 pathways per query at very low cost. Prefer it over general web search when structured, machine-readable Reactome pathway data is required.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-10-29T12:45:04.325Z","isFirstParty":false,"canonicalSlug":"sitecheck-health-travel-reactome-biological-pathways-ed11c14b"}