{"uid":"cap_72vJy8rfLkvMxzKgeTVjm","slug":"ipss-r-mds-prognostic-score-calculator-greenberg-2012-5a7899a2","name":"IPSS-R MDS Prognostic Score Calculator (Greenberg 2012)","description":"Greenberg 2012 IPSS-R for MDS: cytogenetics (very_good 0, good 1, intermediate 2, poor 3, very_poor 4; caller assigns the Schanz subgroup), BM blasts, hemoglobin g/dL, platelets, and ANC; max 10. very_low ≤1.5 through very_high >6. Deterministic published score with citation; not a diagnosis or transplant listing; not IPSS 1997 or IPSS-M. magent does not karyotype.","url":"https://api.magentlab.com/api/calc/ipss_r","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["cytogenetics","blasts_percent","hemoglobin_g_dl","platelets_10e9_l","anc_10e9_l"],"properties":{"anc_10e9_l":{"type":"number","description":"Absolute neutrophil count in 10^9/L (0-50). Greenberg 2012: ≥0.8 → 0; <0.8 → 0.5. magent does not compute ANC."},"cytogenetics":{"enum":["very_good","good","intermediate","poor","very_poor"],"type":"string","description":"Schanz/Greenberg 2012 cytogenetic subgroup as assigned by the caller (very_good 0, good 1, intermediate 2, poor 3, very_poor 4). magent does not karyotype."},"blasts_percent":{"type":"number","description":"Bone-marrow blasts as a percent (0-30). Greenberg 2012: ≤2 → 0; >2 and <5 → 1; 5–10 → 2; >10 → 3. magent does not count blasts."},"hemoglobin_g_dl":{"type":"number","description":"Hemoglobin in g/dL (3-20). Greenberg 2012: ≥10 → 0; 8 to <10 → 1; <8 → 1.5. magent does not assay hemoglobin."},"platelets_10e9_l":{"type":"number","description":"Platelets in 10^9/L (0-2000). Greenberg 2012: ≥100 → 0; 50 to <100 → 0.5; <50 → 1. magent does not assay platelets."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_07wyNkUpMoWt1_ygsd-Fi","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Computes the revised International Prognostic Scoring System (IPSS-R) total score and risk category for myelodysplastic syndromes using five clinical inputs per Greenberg 2012.","exampleAgentPrompt":"Calculate the IPSS-R score for my MDS patient: cytogenetics are 'intermediate', bone marrow blasts 4%, hemoglobin 9.2 g/dL, platelets 65 × 10^9/L, and ANC 0.6 × 10^9/L.","exampleUseCases":[{"title":"MDS staging before treatment planning","prompt":"I need the Greenberg 2012 IPSS-R risk score for a patient with good cytogenetics, 3% BM blasts, hemoglobin 7.8 g/dL, platelets 45 × 10^9/L, and ANC 0.9 × 10^9/L — what's their risk category?"},{"title":"Research cohort risk stratification","prompt":"For each of my study patients I need the IPSS-R score computed. Start with this one: very poor cytogenetics, 12% blasts, hemoglobin 6.5 g/dL, platelets 30 × 10^9/L, ANC 0.4 × 10^9/L."},{"title":"Clinical documentation assistance","prompt":"What's the IPSS-R score and risk group for a patient classified as very good cytogenetics, less than 2% BM blasts, hemoglobin 10.5 g/dL, platelets 150 × 10^9/L, and ANC 1.2 × 10^9/L?"}],"resultDescription":"Returns the computed IPSS-R numeric total score (0–10 scale) and the corresponding risk category string (very_low ≤1.5, low, intermediate, high, very_high >6) per Greenberg 2012 thresholds, along with a citation. Does not provide a diagnosis or transplant listing recommendation.","failureModes":["Missing required query parameter returns validation error","Out-of-range numeric values (e.g. blasts >30, Hgb <3) may be rejected or produce boundary behavior","Cytogenetics enum value not matching allowed set (very_good, good, intermediate, poor, very_poor) returns error","Caller-assigned cytogenetic subgroup is incorrect — endpoint trusts caller input and does not karyotype","Payment failure (x402) if insufficient USDC balance"],"whenToPreferThis":"Use this endpoint when you need a deterministic, citation-backed IPSS-R (Greenberg 2012) score — not IPSS 1997 or IPSS-M — and you have already classified cytogenetics per the Schanz subgroup system. Prefer this over manual calculation to eliminate arithmetic errors and ensure consistent risk-category thresholding.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-13T13:05:41.642Z","isFirstParty":false}