{"uid":"cap_6qPSF88C-fdcTl1LS5kW_","slug":"nadler-1962-blood-volume-estimator-fbf9e5b4","name":"Nadler 1962 Blood Volume Estimator","description":"Nadler 1962 predicted blood volume in liters from height, weight, and sex (separate male and female equations). Deterministic published arithmetic with citation. For adults as published; this tool does not take age. Not a transfusion order, Lemmens–Bernstein–Brodsky estimate, or 70 mL/kg rule of thumb.","url":"https://api.magentlab.com/api/calc/nadler","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["sex"],"properties":{"sex":{"enum":["female","male"],"type":"string","description":"Sex used by Nadler 1962 (separate male and female equations)."},"height_cm":{"type":"number","description":"Height in centimeters. Provide height_cm or height_in."},"height_in":{"type":"number","description":"Height in inches. Converted as cm = in * 2.54."},"weight_kg":{"type":"number","description":"Weight in kilograms. Provide weight_kg or weight_lb."},"weight_lb":{"type":"number","description":"Weight in pounds. Converted as kg = lb * 0.45359237."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":{"type":"json","example":{"path":"/api/calc/nadler","count":2,"items":[{"sex":"male","formula":"nadler","citation":{"id":"nadler-1962","pmid":"21936146","title":"Prediction of blood volume in normal human adults","source":"Surgery. 1962;51(2):224-232","authors":"Nadler SB, Hidalgo JH, Bloch T"},"height_cm":170,"weight_kg":70,"disclaimer":"Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.","blood_volume_l":4.66,"blood_volume_ml":4660,"formula_expression":"BV_L = 0.3669 * H^3 + 0.03219 * W + 0.6041 (male); BV_L = 0.3561 * H^3 + 0.03308 * W + 0.1833 (female); H meters, W kg"},{"sex":"male","formula":"nadler","citation":{"id":"nadler-1962","pmid":"21936146","title":"Prediction of blood volume in normal human adults","source":"Surgery. 1962;51(2):224-232","authors":"Nadler SB, Hidalgo JH, Bloch T"},"height_cm":170,"weight_kg":70,"disclaimer":"Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.","blood_volume_l":4.66,"blood_volume_ml":4660,"formula_expression":"BV_L = 0.3669 * H^3 + 0.03219 * W + 0.6041 (male); BV_L = 0.3561 * H^3 + 0.03308 * W + 0.1833 (female); H meters, W kg"}]}},"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_lwmf4tK8TuA8nunen6ru0","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Estimates total blood volume in liters for adults using the Nadler 1962 equations, given sex, height, and weight","exampleAgentPrompt":"Use the Nadler 1962 equation to estimate blood volume for a male patient who is 178 cm tall and weighs 82 kg.","exampleUseCases":[{"title":"Perioperative blood loss planning","prompt":"Can you estimate the total blood volume for a female patient who is 162 cm tall and weighs 58 kg using the Nadler formula? I need it for surgical planning."},{"title":"ICU fluid management assessment","prompt":"Using the Nadler 1962 blood volume equations, calculate the estimated circulating blood volume for a male patient who is 6 feet tall and weighs 190 pounds."},{"title":"Anemia workup contextualization","prompt":"What's the predicted total blood volume for a 70 kg female who is 5 foot 4, using the Nadler method? I want to put her hemoglobin loss in context."}],"resultDescription":"A numeric estimate of total blood volume in liters computed via the sex-specific Nadler 1962 regression equations, based on the provided height and weight inputs. No age adjustment is applied. Result is deterministic given the same inputs.","failureModes":["Missing required 'sex' parameter returns an error","Neither height_cm/height_in nor weight_kg/weight_lb provided causes a validation error","Invalid sex value (not 'male' or 'female') returns an enum validation error","Extreme anthropometric values outside the original study's adult range may produce biologically implausible outputs without a warning","Payment not included or insufficient USDC results in 402 payment required response"],"whenToPreferThis":"Use this endpoint when you need the specific Nadler 1962 published equations for adult blood volume estimation from height, weight, and sex — particularly when citeable, deterministic arithmetic is required. Prefer this over the 70 mL/kg rule of thumb when individualized anthropometric data is available. Not appropriate for pediatric patients, for whom age-adjusted formulas are needed, nor as a substitute for direct blood volume measurement.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-15T01:17:00.465Z","isFirstParty":false}