{"uid":"cap_6JbAln_JREl26_PnKd37R","slug":"pecarn-febrile-infant-low-risk-rule-kuppermann-2019-bac95220","name":"PECARN Febrile Infant Low-Risk Rule (Kuppermann 2019)","description":"Kuppermann 2019 PECARN prediction rule for febrile infants 60 days and younger. Low-risk only if all three hold: caller-assigned negative urinalysis, ANC 4090/uL or less, and serum procalcitonin 1.71 ng/mL or less. Age 0-60 pins the published population and is not a tree variable. Returns low_risk. magent does not assay UA, ANC, or PCT. Not Rochester, Boston, Philadelphia, Step-by-Step, later AAP/PECARN cutoffs, or pecarn-head. Not a medical device and not a discharge or LP order.","url":"https://api.magentlab.com/api/calc/pecarn_febrile","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["age_days","negative_urinalysis","anc_per_ul","pct_ng_ml"],"properties":{"age_days":{"type":"integer","description":"Chronological age in days (integer 0-60). Kuppermann 2019 studied febrile infants 60 days and younger. Age pins the published population and is not a tree variable; age 0 and age 60 can both be low-risk when the three laboratory criteria hold."},"pct_ng_ml":{"type":"number","description":"Serum procalcitonin in ng/mL. Range 0.01-100. Low-risk requires 1.71 ng/mL or less (1.71 meets; 1.72 does not). magent does not assay procalcitonin."},"anc_per_ul":{"type":"number","description":"Absolute neutrophil count in cells/µL. Range 0-100000. Low-risk requires ANC 4090/µL or less (4090 meets; 4091 does not). magent does not assay ANC."},"negative_urinalysis":{"type":"boolean","description":"Caller-assigned negative urinalysis as used in Kuppermann 2019. true means the UA is negative. true or false. magent does not assay UA."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_MLuIUJHOPyCJa0AjqdjBT","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Applies the Kuppermann 2019 PECARN prediction rule to classify febrile infants ≤60 days old as low-risk or not, based on urinalysis, ANC, and procalcitonin values.","exampleAgentPrompt":"Run the Kuppermann 2019 PECARN febrile infant rule for a 32-day-old: the urinalysis is negative, ANC is 3800 cells/µL, and procalcitonin is 1.2 ng/mL — is this infant low-risk?","exampleUseCases":[{"title":"ED triage for febrile neonate","prompt":"I have a 21-day-old febrile infant in the ED — urinalysis is negative, ANC came back at 2900, and procalcitonin is 0.85 ng/mL. Run the Kuppermann 2019 PECARN rule and tell me if the baby meets low-risk criteria."},{"title":"Borderline procalcitonin decision support","prompt":"My patient is a 58-day-old with fever — UA is negative, ANC is 4000, but procalcitonin is 1.71 ng/mL exactly. Does this infant qualify as low-risk under the PECARN 2019 febrile infant rule?"},{"title":"Elevated ANC ruling out low-risk","prompt":"I need to check a 45-day-old febrile baby against the Kuppermann 2019 PECARN criteria: UA is negative, ANC is 5200 cells/µL, procalcitonin is 0.5 ng/mL — does the infant meet low-risk classification?"}],"resultDescription":"Returns a low_risk indicator (true or false) based on whether all three Kuppermann 2019 PECARN criteria are simultaneously met: caller-assigned negative urinalysis, ANC ≤4090 cells/µL, and procalcitonin ≤1.71 ng/mL. Does not perform laboratory assays; it only applies the decision rule to caller-provided values.","failureModes":["age_days outside 0-60 range returns validation error","pct_ng_ml outside 0.01-100 range returns validation error","anc_per_ul outside 0-100000 returns validation error","missing required query parameters returns 400-level error","payment failure via x402 protocol returns 402 Payment Required"],"whenToPreferThis":"Use this endpoint specifically when you need to apply the Kuppermann 2019 PECARN three-variable febrile infant rule (negative UA + ANC ≤4090 + PCT ≤1.71) to infants 0-60 days old. Prefer this over other febrile infant rules (Rochester, Boston, Philadelphia, Step-by-Step) when the clinical workflow uses procalcitonin alongside ANC and UA. Do not use for infants older than 60 days, for head injury PECARN, or when laboratory values have not yet been obtained.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T19:06:38.464Z","isFirstParty":false}