{"uid":"cap_6IRYlh24YaGfH0XQKfBOW","slug":"magent-perioperative-doac-interruption-calculator-douketis-2022-accp-bd6b8060","name":"magent Perioperative DOAC Interruption Calculator (Douketis 2022 ACCP)","description":"Douketis 2022 ACCP elective perioperative DOAC interruption (PAUSE-style, recommendations 22-25). Returns hold_days_before and resume_days_after from INN (apixaban, rivaroxaban, edoxaban, dabigatran) and bleed_risk. dabigatran also needs caller-assigned CrCl. heparin_bridge is always false (recommendation 26). Not warfarin, not urgent surgery, not a prescription. magent does not assay CrCl.","url":"https://api.magentlab.com/api/calc/periop_doac","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["doac","bleed_risk"],"properties":{"doac":{"enum":["apixaban","rivaroxaban","edoxaban","dabigatran"],"type":"string","description":"Direct oral anticoagulant INN, case-insensitive: apixaban, rivaroxaban, edoxaban, or dabigatran. Elective procedures only. Not warfarin or a VKA."},"bleed_risk":{"enum":["low_to_moderate","high"],"type":"string","description":"Procedure bleed-risk category from Douketis 2022, case-insensitive: low_to_moderate or high. Caller assigns the category. Not urgent surgery."},"crcl_ml_min":{"type":"number","description":"Caller-assigned creatinine clearance in mL/min (15-120). Required only when doac is dabigatran. Must be absent for apixaban, rivaroxaban, and edoxaban. magent does not assay CrCl."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_vKWbRkKKiiaFga-T8BtGV","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Returns hold-before and resume-after day counts for elective perioperative DOAC interruption based on drug and procedure bleed risk, per Douketis 2022 ACCP PAUSE-style recommendations 22-25.","exampleAgentPrompt":"My patient is on apixaban and is having an elective high-bleed-risk procedure — using the Douketis 2022 ACCP PAUSE recommendations, how many days before surgery should we hold it and when can we restart?","exampleUseCases":[{"title":"Elective knee replacement DOAC hold","prompt":"My patient takes rivaroxaban and is scheduled for an elective knee replacement, which is high bleed risk — per Douketis 2022, how many days before the operation should they stop rivaroxaban and when can they resume?"},{"title":"Dabigatran hold with impaired renal function","prompt":"I need the perioperative DOAC interruption schedule for a patient on dabigatran with a CrCl of 40 mL/min going in for a low-to-moderate bleed-risk elective procedure — give me the hold and restart days from the ACCP PAUSE guidelines."},{"title":"Heparin bridge decision for edoxaban patient","prompt":"Do I need to bridge with heparin when holding edoxaban for an elective low-to-moderate bleed-risk surgery, and what are the recommended hold and resume days per Douketis 2022?"}],"resultDescription":"Returns hold_days_before (number of days to stop the DOAC prior to surgery) and resume_days_after (number of days post-procedure before restarting), plus heparin_bridge (always false per recommendation 26). Specific to the given DOAC and bleed risk tier, with dabigatran values further stratified by caller-supplied CrCl.","failureModes":["Missing required bleed_risk parameter returns validation error","crcl_ml_min provided for apixaban/rivaroxaban/edoxaban returns error (must be absent)","crcl_ml_min absent for dabigatran returns error (required for that drug)","crcl_ml_min outside 15-120 range may return validation error","Invalid/unrecognized DOAC name returns error","Warfarin or VKA submitted — endpoint does not support these agents","Urgent or emergent surgery context not supported"],"whenToPreferThis":"Use this endpoint when you need guideline-concordant PAUSE-style hold and restart day counts for elective procedures involving a DOAC (apixaban, rivaroxaban, edoxaban, or dabigatran) and you already know the procedure bleed risk category and, for dabigatran, the patient's CrCl. Prefer this over general anticoagulation references when you need a structured, machine-readable output aligned to Douketis 2022 ACCP recommendations 22-25. Do not use for warfarin, urgent surgery, or when CrCl needs to be computed.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T13:06:50.661Z","isFirstParty":false}