{"uid":"cap_5LjYNksAGqwkxyF_3GtbI","slug":"aha-acc-2018-very-high-risk-ascvd-classifier-table-4-cb526d78","name":"AHA/ACC 2018 Very High-Risk ASCVD Classifier (Table 4)","description":"AHA/ACC 2018 Table 4 very high-risk ASCVD for known clinical ASCVD. Very high-risk if ≥2 major events (recent ACS, prior MI, ischemic stroke, symptomatic PAD) or 1 major event and ≥2 high-risk conditions (age ≥65, heterozygous FH, CABG/PCI outside those events, diabetes, hypertension, CKD eGFR 15-59, current smoking, LDL-C ≥100 on max statin and ezetimibe, congestive HF). Not PCE. Not a statin, ezetimibe, or PCSK9 order. magent does not diagnose ASCVD or measure ABI or LDL-C.","url":"https://api.magentlab.com/api/calc/ascvd_vhr","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["age","recent_acs","history_mi","ischemic_stroke","symptomatic_pad","heterozygous_fh","prior_cabg_or_pci_outside_major","diabetes","hypertension","ckd_egfr_15_to_59","current_smoking","ldl_c_ge_100_on_max_statin_ezetimibe","congestive_hf"],"properties":{"age":{"type":"integer","description":"Age in years (18-120). ≥65 is an AHA/ACC 2018 Table 4 high-risk condition. magent does not assign age."},"diabetes":{"type":"boolean","description":"Diabetes mellitus as assigned by the caller (AHA/ACC 2018 Table 4 high-risk condition). true or false. magent does not diagnose diabetes."},"history_mi":{"type":"boolean","description":"History of MI other than a caller-assigned recent ACS as assigned by the caller (AHA/ACC 2018 Table 4 major ASCVD event). true or false. magent does not diagnose MI."},"recent_acs":{"type":"boolean","description":"Recent ACS within the past 12 months as assigned by the caller (AHA/ACC 2018 Table 4 major ASCVD event). true or false. magent does not date ACS."},"hypertension":{"type":"boolean","description":"Hypertension as assigned by the caller (AHA/ACC 2018 Table 4 high-risk condition). true or false. magent does not measure blood pressure."},"congestive_hf":{"type":"boolean","description":"History of congestive HF as assigned by the caller (AHA/ACC 2018 Table 4 high-risk condition). true or false. magent does not diagnose HF."},"current_smoking":{"type":"boolean","description":"Current smoking as assigned by the caller (AHA/ACC 2018 Table 4 high-risk condition). true or false. magent does not assign smoking status."},"heterozygous_fh":{"type":"boolean","description":"Heterozygous familial hypercholesterolemia as assigned by the caller (AHA/ACC 2018 Table 4 high-risk condition). true or false. magent does not diagnose FH."},"ischemic_stroke":{"type":"boolean","description":"History of ischemic stroke as assigned by the caller (AHA/ACC 2018 Table 4 major ASCVD event). true or false. magent does not diagnose stroke."},"symptomatic_pad":{"type":"boolean","description":"Symptomatic PAD as assigned by the caller from the Table 4 row (claudication with ABI <0.85, or previous revascularization or amputation). true or false. magent does not measure ABI."},"ckd_egfr_15_to_59":{"type":"boolean","description":"CKD with eGFR 15–59 mL/min/1.73 m² as assigned by the caller (AHA/ACC 2018 Table 4 printed band). true or false. magent does not compute eGFR."},"prior_cabg_or_pci_outside_major":{"type":"boolean","description":"Prior CABG or PCI outside the major ASCVD event(s) as assigned by the caller (AHA/ACC 2018 Table 4 high-risk condition). true or false. magent does not read an operative note."},"ldl_c_ge_100_on_max_statin_ezetimibe":{"type":"boolean","description":"Persistently elevated LDL-C ≥100 mg/dL (≥2.6 mmol/L) despite maximally tolerated statin and ezetimibe as assigned by the caller (AHA/ACC 2018 Table 4 high-risk condition). true or false. magent does not assay LDL-C."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_noj-S5oGQW2ag0iN5q-Iu","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Classifies a patient as very high-risk for ASCVD per AHA/ACC 2018 Table 4 criteria based on major events and high-risk conditions","exampleAgentPrompt":"Does my 68-year-old patient with a recent ACS 6 months ago, a prior MI, diabetes, and hypertension qualify as very high-risk ASCVD under the AHA/ACC 2018 Table 4 criteria? No FH, no CABG or PCI outside those events, not currently smoking, no CKD, LDL under 100, no congestive HF.","exampleUseCases":[{"title":"PCSK9 eligibility pre-check for cardiologist","prompt":"My patient is 71 years old with a history of ischemic stroke and symptomatic PAD, plus hypertension and current smoking. No recent ACS, no prior MI, no diabetes, no FH, no prior CABG or PCI, no CKD, LDL is fine, no HF. Do they meet AHA/ACC 2018 very high-risk ASCVD criteria?"},{"title":"Post-discharge ASCVD risk stratification","prompt":"A 60-year-old patient was just discharged after an ACS eight months ago. They also have heterozygous FH and congestive HF, but no prior MI, no stroke, no PAD, no diabetes, not hypertensive, not smoking, no CKD, LDL is controlled. Are they very high-risk by AHA/ACC 2018 Table 4?"},{"title":"Automated EHR risk flag for lipid clinic","prompt":"Flag this 55-year-old patient: prior MI confirmed, no recent ACS, no stroke, no PAD, diabetes yes, hypertension yes, CKD with eGFR between 15 and 59, currently smoking, LDL-C is 105 on max statin plus ezetimibe, no FH, no prior CABG or PCI outside major events, no congestive HF. Is this a very high-risk ASCVD patient per the 2018 AHA/ACC Table 4?"}],"resultDescription":"Returns a boolean or structured classification indicating whether the patient meets AHA/ACC 2018 Table 4 very high-risk ASCVD criteria, based on the count of qualifying major ASCVD events and high-risk conditions supplied by the caller","failureModes":["Missing required query parameters (age, any of the boolean flags) returns a 400 or validation error","Non-integer age or out-of-range values may cause rejection","Boolean fields passed as non-boolean strings may fail validation","Misinterpretation of endpoint scope: it does not diagnose conditions, measure labs, or compute PCE risk — callers must pre-assign all clinical values"],"whenToPreferThis":"Use this endpoint when you need to apply the exact AHA/ACC 2018 Table 4 very high-risk ASCVD criteria for a patient with known clinical ASCVD, particularly to guide secondary prevention intensity or PCSK9 inhibitor eligibility. Prefer this over PCE-based calculators (which are for primary prevention) or general risk scores when the patient already has established ASCVD and you need to distinguish very high-risk from high-risk for guideline-directed therapy decisions.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T06:46:24.521Z","isFirstParty":false}