{"uid":"cap_3KA4LAgbZyfiVx1mFnzks","slug":"khan-2024-aha-prevent-base-10-year-total-cvd-risk-calculator-f392a1bd","name":"Khan 2024 AHA PREVENT Base 10-Year Total CVD Risk Calculator","description":"Khan 2024 AHA PREVENT base 10-year total CVD percent (ASCVD plus heart failure) for age 30-79 from sex, lipids, treated systolic BP, diabetes, smoking, eGFR, BMI, antihypertensive, and statin. Sex-specific, race-free Table S12 coefficients. Not 30-year, not ASCVD-only, not HF-only, not 2013 PCE, not SCORE2, not a diagnosis or statin order. magent does not assay lipids.","url":"https://api.magentlab.com/api/calc/prevent","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["age","sex","total_cholesterol_mg_dl","hdl_mg_dl","sbp_mm_hg","antihypertensive","statin","diabetes","smoker","egfr_ml_min_1_73m2","bmi_kg_m2"],"properties":{"age":{"type":"integer","description":"Age in years (integer 30-79). Khan 2024 PREVENT base 10-year total CVD is for ages 30-79. Not 30-year PREVENT (that horizon is not returned)."},"sex":{"enum":["female","male"],"type":"string","description":"Sex used by the sex-specific Table S12 base 10-year total-CVD coefficients (female or male). Not race. PREVENT is race-free."},"smoker":{"type":"boolean","description":"Current cigarette smoking as assigned by the caller (true or false). magent does not take a smoking history."},"statin":{"type":"boolean","description":"Current statin use as assigned by the caller (true or false). Adds the Table S12 statin term and the statin × non-HDL interaction."},"diabetes":{"type":"boolean","description":"Diabetes as assigned by the caller (true or false). Adds the Table S12 diabetes term and the age × diabetes interaction. Not the optional HbA1c add-on equation."},"bmi_kg_m2":{"type":"number","description":"Body-mass index in kg/m2 (10-80). Required Khan 2024 predictor. Table S12 base 10-year total-CVD BMI coefficients are 0 (BMI enters the HF-only equations, which this tool does not return)."},"hdl_mg_dl":{"type":"number","description":"HDL cholesterol in mg/dL (5-150). Converted as mg/dL*0.02586 to mmol/L. Enters as (HDL-1.3)/0.3. magent does not assay lipids."},"sbp_mm_hg":{"type":"number","description":"Systolic blood pressure in mm Hg (50-250). Piecewise around 110 mm Hg, with a treated-SBP interaction when antihypertensive is true. magent does not measure blood pressure."},"antihypertensive":{"type":"boolean","description":"Current antihypertensive treatment as assigned by the caller (true or false). Adds the Table S12 antihypertensive term and the treated SBP interaction."},"egfr_ml_min_1_73m2":{"type":"number","description":"Caller-assigned eGFR in mL/min/1.73m2 (5-200). Piecewise around 60. magent does not compute MDRD or CKD-EPI."},"total_cholesterol_mg_dl":{"type":"number","description":"Total cholesterol in mg/dL (50-800). Converted as mg/dL*0.02586 to mmol/L. Enters as non-HDL (TC-HDL) centered at 3.5 mmol/L. magent does not assay lipids."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_ZO40RJp2sgvtLL-u11e--","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Computes the AHA PREVENT model's base 10-year total cardiovascular disease (ASCVD + heart failure) risk percentage for adults aged 30–79 using sex-specific, race-free Table S12 coefficients.","exampleAgentPrompt":"What's the 10-year total CVD risk using the AHA PREVENT model for a 58-year-old female who doesn't smoke, has total cholesterol 210 mg/dL, HDL 55 mg/dL, systolic BP 138 mmHg on antihypertensives, no statin, no diabetes, eGFR 72 ml/min/1.73m2, and BMI 27?","exampleUseCases":[{"title":"Primary prevention statin decision support","prompt":"I need to figure out a 64-year-old male patient's 10-year total cardiovascular risk with the PREVENT 2024 model — he has total cholesterol 240 mg/dL, HDL 42 mg/dL, systolic BP 145 mmHg not on any BP meds, he's a current smoker, no statin, has diabetes type 2, eGFR 65, BMI 31."},{"title":"Pre-visit cardiovascular risk report","prompt":"Can you calculate the AHA PREVENT 10-year combined ASCVD and heart failure risk for a 47-year-old woman: total cholesterol 195 mg/dL, HDL 60 mg/dL, systolic BP 122 mmHg on antihypertensive therapy, on a statin, non-smoker, no diabetes, eGFR 88, BMI 24?"},{"title":"Monitoring treatment impact on risk score","prompt":"Run the PREVENT base 10-year total CVD risk for a 52-year-old male — total cholesterol 178 mg/dL, HDL 48 mg/dL, treated systolic BP 128 mmHg on antihypertensives, currently on a statin, non-smoker, diabetic, eGFR 58, BMI 29 — so we can see how his risk has changed after starting statin therapy."}],"resultDescription":"Returns the Khan 2024 AHA PREVENT base 10-year total CVD risk as a percentage (ASCVD plus heart failure combined), computed using sex-specific Table S12 coefficients. The result does not include the 30-year horizon, standalone ASCVD-only risk, standalone HF-only risk, or optional HbA1c add-on terms.","failureModes":["Age outside 30–79 range returns an error or invalid result","Sex value not 'female' or 'male' returns a validation error","Cholesterol, SBP, eGFR, or BMI values outside expected ranges cause rejection","Missing any required query parameter returns a 400 bad request","Payment not included or insufficient USDC returns 402 Payment Required","Lipid values provided in mmol/L instead of mg/dL will produce incorrect results (conversion is internal)"],"whenToPreferThis":"Use this endpoint when you specifically need the Khan 2024 AHA PREVENT base 10-year total CVD risk (ASCVD + heart failure combined) for adults aged 30–79, using sex-specific and race-free Table S12 coefficients. Prefer it over the 2013 Pooled Cohort Equations (PCE) when a race-free, updated model is required. Choose it over SCORE2 when working with a US-centric or AHA-guideline-aligned workflow. Do not use this endpoint when you need the 30-year PREVENT horizon, standalone HF-only risk, HbA1c-augmented equations, or a statin prescribing recommendation — it computes risk only.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T13:05:50.511Z","isFirstParty":false}