{"uid":"cap_1e5NWVJ6cNz47r--j0exN","slug":"magent-alteplase-stroke-dose-calculator-ninds-1995-f329abfb","name":"magent Alteplase Stroke Dose Calculator (NINDS 1995)","description":"NINDS 1995 IV alteplase milligram arithmetic from weight: total_mg = min(0.9 × weight_kg, 90), 10% bolus, 90% infusion over 60 minutes. Reports milligrams and whether the 90 mg cap applied. Not a medical device, not a prescription, not an eligibility screen, and not tenecteplase.","url":"https://api.magentlab.com/api/calc/alteplase_stroke","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["weight_kg"],"properties":{"weight_kg":{"type":"number","description":"Weight in kilograms (1-500). NINDS 1995 dose is 0.9 mg/kg, maximum 90 mg. magent clamp, not an eligibility band."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_WqoEzrW_tERR60qXVc9VZ","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Calculates the NINDS 1995 IV alteplase dose for ischemic stroke from patient weight: total_mg = min(0.9 × weight_kg, 90), with 10% bolus and 90% 60-minute infusion breakdown.","exampleAgentPrompt":"Calculate the NINDS 1995 alteplase dose for a stroke patient weighing 85 kg — I need the total milligrams, the 10% bolus amount, the 90% infusion amount, and whether the 90 mg cap kicked in.","exampleUseCases":[{"title":"Stroke team dose verification at bedside","prompt":"Our patient just came in with acute ischemic stroke and weighs 68 kg — calculate their alteplase dose using the NINDS 1995 protocol and tell me the bolus and infusion amounts."},{"title":"Heavy patient cap check","prompt":"Patient weighs 110 kg. What's the alteplase dose under the NINDS 1995 protocol? Does the 90 mg cap apply, and what's the split between bolus and infusion?"},{"title":"Lightweight patient dosing","prompt":"Calculate the IV alteplase stroke dose for a 52 kg patient using NINDS 1995 — show me the total milligrams, 10% bolus, and 90% infusion over 60 minutes."}],"resultDescription":"Returns the total alteplase dose in milligrams (0.9 × weight_kg, capped at 90 mg), the 10% bolus dose in mg, the 90% infusion dose in mg to be given over 60 minutes, and a boolean or flag indicating whether the 90 mg maximum cap was applied.","failureModes":["Missing weight_kg parameter returns a validation error","weight_kg outside plausible range (e.g. 0, negative, or extremely high values) may return an error or clamped result","Non-numeric weight_kg causes a schema validation failure","Service unavailable or payment not processed returns HTTP 402 or 5xx"],"whenToPreferThis":"Use this endpoint when you need fast, reliable arithmetic for the NINDS 1995 IV alteplase dosing protocol in acute ischemic stroke — specifically the 0.9 mg/kg formula capped at 90 mg with the 10%/90% bolus/infusion split. This is NOT for tenecteplase, NOT an eligibility screen, and NOT a medical device — it is purely a dosing arithmetic calculator. Prefer this over manual calculation to avoid arithmetic errors in high-stakes clinical workflow automation.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T13:06:20.589Z","isFirstParty":false}