{"uid":"cap_1SAzR8MexXiHyz4ZEXv8q","slug":"brue-calculator-tieder-2016-1bbb0c53","name":"BRUE Calculator (Tieder 2016)","description":"BRUE (Tieder 2016 AAP). brue is true iff the infant is younger than 1 year, the episode was sudden, brief, and now resolved, no explanation remains after appropriate history and physical examination, and at least one of: cyanosis or pallor; absent, decreased, or irregular breathing; marked change in tone; altered level of responsiveness. feature_count is 0-4. Caller assigns seven flags. magent does not examine the infant. Not a diagnosis, not ALTE, not SIDS.","url":"https://api.magentlab.com/api/calc/brue","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["age_under_1_year","sudden_brief_now_resolved","cyanosis_or_pallor","absent_decreased_irregular_breathing","marked_tone_change","altered_responsiveness","unexplained_after_history_exam"],"properties":{"age_under_1_year":{"type":"boolean","description":"Infant younger than 1 year as assigned by the caller (Tieder 2016 BRUE definition). true or false. magent does not examine the infant or take an age in days."},"cyanosis_or_pallor":{"type":"boolean","description":"Cyanosis or pallor during the episode (one of four event features; at least one required). true or false as assigned by the caller. magent does not examine the infant."},"marked_tone_change":{"type":"boolean","description":"Marked change in tone (hyper- or hypotonia) during the episode (one of four event features; at least one required). true or false as assigned by the caller."},"altered_responsiveness":{"type":"boolean","description":"Altered level of responsiveness during the episode (one of four event features; at least one required). true or false as assigned by the caller."},"sudden_brief_now_resolved":{"type":"boolean","description":"Observer reports a sudden, brief, and now resolved episode as assigned by the caller. true or false. magent does not take a history."},"unexplained_after_history_exam":{"type":"boolean","description":"No explanation remains after appropriate history and physical examination as assigned by the caller. true means unexplained and is required for BRUE. true or false. magent does not examine the infant."},"absent_decreased_irregular_breathing":{"type":"boolean","description":"Absent, decreased, or irregular breathing during the episode (one of four event features; at least one required). true or false as assigned by the caller."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_s6j3bGYPyoL_xRVLkKoeQ","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Evaluates whether an infant episode meets the AAP 2016 BRUE (Brief Resolved Unexplained Event) criteria based on seven caller-assigned flags","exampleAgentPrompt":"Check if this baby's episode meets BRUE criteria: the infant is under 1 year old, the episode was sudden, brief, and fully resolved, there's no explanation after history and exam, and during the event there was cyanosis and absent breathing but no tone change or altered responsiveness.","exampleUseCases":[{"title":"ED triage for infant apnea episode","prompt":"A 3-month-old came in after a witnessed episode of apnea that resolved on its own. The episode was sudden and brief, no explanation found after exam, infant is under 1 year — there was absent breathing and pallor but no tone change and no altered responsiveness. Does this meet BRUE criteria?"},{"title":"Outpatient pediatrician BRUE screening","prompt":"I'm seeing a 7-month-old whose parents describe a brief episode of limpness and unresponsiveness that resolved spontaneously. Episode was sudden and unexplained after my history and physical. There was marked tone change and altered responsiveness, no cyanosis or breathing irregularity. Calculate the BRUE feature count for this patient."},{"title":"Clinical documentation and risk stratification","prompt":"Help me confirm BRUE status for a 10-month-old: under 1 year — yes, sudden and brief and resolved — yes, unexplained after history and exam — yes, cyanosis or pallor — no, absent or irregular breathing — yes, marked tone change — yes, altered responsiveness — no. What's the BRUE result and feature count?"}],"resultDescription":"Returns a 'brue' boolean indicating whether all BRUE criteria are met, and a 'feature_count' integer (0–4) counting how many of the four event features (cyanosis/pallor, absent/decreased/irregular breathing, marked tone change, altered responsiveness) are present. Does not provide diagnosis, risk stratification, or management recommendations.","failureModes":["Missing required query parameters returns an error","All four event feature flags set to false still evaluates but brue may be false due to absence of required feature","unexplained_after_history_exam=false forces brue=false regardless of other flags","age_under_1_year=false forces brue=false","Caller assigns flags incorrectly — endpoint accepts any boolean values without clinical validation"],"whenToPreferThis":"Use this endpoint when you need a fast, deterministic computation of whether a clinical presentation meets the AAP 2016 BRUE definition (Tieder et al.), and you have already gathered all seven clinical flags from history and physical examination. This is not a substitute for clinical judgment and does not perform its own examination. Prefer this over manual checklist application when integrating into an EHR workflow, a clinical decision support agent, or a documentation tool that needs to programmatically classify infant episodes.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T13:09:05.928Z","isFirstParty":false}