{"uid":"cap_-3p3zURE_lg8ipgX0TM8N","slug":"pompe-c-30-day-mortality-calculator-for-cancer-acute-pe-1ece5d35","name":"POMPE-C 30-Day Mortality Calculator for Cancer + Acute PE","description":"Kline 2012 POMPE-C 30-day mortality probability for active cancer plus acute PE. Logistic from DNR, respiratory distress, unilateral limb swelling, altered mental status, heart rate >99, respiratory rate, room-air SpO2, and weight in pounds (intercept 3.718). Bands: low <=5%, high >50%, else intermediate. Not a PE or cancer diagnosis, not integer points, not a dose.","url":"https://api.magentlab.com/api/calc/pompe_c","method":"GET","headers":{},"bodySchema":{"type":"object","$schema":"https://json-schema.org/draft/2020-12/schema","required":["input"],"properties":{"input":{"type":"object","required":["type","method"],"properties":{"type":{"type":"string","const":"http"},"method":{"enum":["GET","HEAD","DELETE"],"type":"string"},"headers":{"type":"object","additionalProperties":{"type":"string"}},"queryParams":{"type":"object","required":["dnr","respiratory_distress","unilateral_leg_swelling","altered_mental_status","heart_rate_gt_99","respiratory_rate","spo2_percent","weight_lb"],"properties":{"dnr":{"type":"boolean","description":"Do-not-resuscitate status as assigned by the caller (Kline 2012: new or existing verbal or written desire not to be resuscitated). true or false. magent does not read an advance directive."},"weight_lb":{"type":"number","description":"Body weight in pounds (2-1100), measured or by patient estimate as in Kline 2012. Pounds enter the logistic directly. magent does not convert from kilograms."},"spo2_percent":{"type":"number","description":"Most recent pulse oximetry on room air, percent (50-100). Continuous predictor in the Kline 2012 prototype logistic. magent does not measure saturation."},"heart_rate_gt_99":{"type":"boolean","description":"Heart rate documented over 99 beats/min in the previous six hours, as assigned by the caller. true or false. magent does not take a pulse."},"respiratory_rate":{"type":"integer","description":"Highest documented respiratory rate in breaths/min within the previous six hours (integer 4-80). Continuous predictor in the Kline 2012 prototype logistic."},"respiratory_distress":{"type":"boolean","description":"Respiratory distress as assigned by the caller (Kline 2012: obvious anxiety from dyspnea or increased work of breathing). true or false. magent does not examine the patient."},"altered_mental_status":{"type":"boolean","description":"Altered mental status as assigned by the caller (Kline 2012: acute impairment in consciousness, new disorientation, delirium, or confusion). true or false. magent does not examine the patient."},"unilateral_leg_swelling":{"type":"boolean","description":"Unilateral limb swelling as assigned by the caller (Kline 2012: new noticeable arm or leg asymmetry). true or false. magent does not examine the limbs."}}}},"additionalProperties":false},"output":{"type":"object","required":["type"],"properties":{"type":{"type":"string"},"example":{"type":"object"}}}}},"responseSchema":null,"example":null,"exampleRequest":null,"tags":["x402"],"displayCostAmount":"0.005","displayCostAsset":"USDC","priceDynamic":false,"priceHint":null,"priceStatus":"priced","priceSource":"probe","requiresHandshake":false,"reviewCount":0,"rating":{"score":"0.00","successRate":"0.00","reviews":0,"stars":null,"state":"unrated"},"availabilityStatus":"unknown","priceObserved":null,"sessionDeposit":null,"pricing":{"kind":"static","summary":"$0.005/call","primary":{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"},"accepted":[{"kind":"static","protocol":"x402","network":"base","amountUsd":"0.005","per":"call","confidence":"exact"}]},"paymentMethods":[{"uid":"pm_jS7F9yFBNzgPmLVOUu3OU","protocol":"x402","methodType":"crypto","chain":"base","mode":"charge","costAmount":"0.005","costPer":"request","priority":0,"asset":"0x833589fCD6eDb6E08f4c7C32D4f71b54bdA02913","unit":"request","depositMicros":null,"planRef":null}],"brandName":null,"brandSlug":null,"brandBaseUrl":null,"brandDocsUrl":null,"whatItDoes":"Computes Kline 2012 POMPE-C logistic regression probability of 30-day mortality in patients with active cancer and acute pulmonary embolism, with risk band classification.","exampleAgentPrompt":"Calculate the POMPE-C 30-day mortality probability for a cancer patient with acute PE: they are not DNR, have visible respiratory distress, no unilateral leg swelling, no altered mental status, heart rate over 99, respiratory rate of 24 breaths/min, room-air SpO2 of 92%, and weight 185 pounds.","exampleUseCases":[{"title":"ED triage for cancer patient with PE","prompt":"My patient with active lung cancer just presented with acute PE. She's not DNR, she's in obvious respiratory distress, no unilateral leg swelling, she's alert, heart rate was 108 last hour, respiratory rate is 22, her room-air sat is 90%, and she weighs 160 pounds. Can you run the POMPE-C to get her 30-day mortality probability and risk band?"},{"title":"ICU disposition decision support","prompt":"I need a POMPE-C score for disposition planning — active cancer patient, new verbal DNR in place, no respiratory distress, has unilateral left leg swelling, no altered mental status, heart rate 95, respiratory rate 18, SpO2 95% on room air, 210 pounds. What's his 30-day mortality probability and is that low, intermediate, or high risk?"},{"title":"Oncology rapid mortality stratification","prompt":"Run a Kline 2012 POMPE-C calculation: patient has active cancer and confirmed PE, no DNR order, no respiratory distress, no leg swelling, no altered mental status, heart rate under 100, respiratory rate 16, room-air SpO2 is 97%, weight 140 pounds. Give me the probability and which risk band that falls in."}],"resultDescription":"Returns the Kline 2012 POMPE-C logistic regression–derived probability of 30-day mortality (as a decimal or percentage) and a risk band classification: low (≤5%), high (>50%), or intermediate (between 5% and 50%). Does not diagnose PE or cancer, does not output integer points, and does not recommend a dose.","failureModes":["Missing required query parameter returns an error — all eight clinical variables are mandatory","weight_lb outside 2–1100 range may be rejected or produce unreliable output","spo2_percent outside 50–100 range may be rejected","respiratory_rate outside 4–80 integer range may be rejected","Boolean fields passed as strings instead of true booleans may cause parsing errors","Payment failure (402) if x402 USDC payment is not provided or insufficient"],"whenToPreferThis":"Use this endpoint when you need to compute the Kline 2012 POMPE-C logistic regression score specifically for patients with both active cancer and acute PE to estimate 30-day mortality probability. Prefer this over generic PE severity scores (e.g., PESI, sPESI) when the patient has active cancer, as POMPE-C was derived specifically for that population. This endpoint is a continuous probability calculator with risk band output, not a point-based integer scoring system.","instructions":null,"reviewSummary":null,"reviewSummaryHighlights":null,"reviewSummaryConcerns":null,"reviewSummaryGeneratedAt":null,"activationCount":0,"lastUsedAt":null,"lastSuccessfullyRanAt":null,"lastHealthCheckAt":"2026-09-14T12:57:17.565Z","isFirstParty":false}